Table 3—

Plasma glucose, insulin and HbA1c values during the metabolic day profile before (baseline) and after 4 weeks of HGI or LGI diets

HGI diet
LGI diet
Baseline*4 weeks*Baseline*4 weeks*
Glycemia (mmol/l)
    Fasting (0 min)9.4 ± 0.59.8 ± 0.610.1 ± 0.89.19 ± 0.7§**
    Morning peak (60–0 min)4.2 ± 0.33.7 ± 0.32.8 ± 0.33.3 ± 0.5
    AUC (mmol · l−1 · 8 h−1)527 ± 57520 ± 61358 ± 90274 ± 32
Insulinemia (pmol/l)
    Fasting (0 min)113 ± 11125 ± 16111 ± 19123 ± 22
    Morning peak (60–0 min)142 ± 15171 ± 19126 ± 25149 ± 27
    AUC/102 (pmol · l−1 · 8 h−1)845 ± 10754 ± 27646 ± 36618 ± 65
HbA1c (%)7.45 ± 0.357.57 ± 0.357.56 ± 0.367.17 ± 0.39§**
  • Data are means ± SE. n = 11.

  • *

    * Results during the 8-h metabolic profile before (baseline data) or after (4-week data) the chronic nutritional periods. During the 8-h metabolic profile, values were taken just before (data in the fasting state, 0 min) or after the HGI or LGI meals, respectively.

  • Data followed by different superscripts († and ‡) for a row are significantly different at P < 0.05.

  • §

    § Changes during the dietary periods (Δ = baseline data − 4-week data, HGI vs. LGI).

  • P < 0.05 by multiple ANOVA;

  • **

    ** P < 0.01, for Δ.