Table 4—

Fasting plasma lipid and lipoprotein concentrations, total fat and lean body mass measured by DEXA, and plasma PAI-1 at baseline and after 4 weeks of HGI or LGI diets

HGI diet
LGI diet
Baseline*4 weeks*Baseline*4 weeks*
Total cholesterol (mmol/l)4.79 ± 0.244.90 ± 0.205.33 ± 0.434.46 ± 0.29§**
LDL cholesterol (mmol/l)2.89 ± 0.263.03 ± 0.213.46 ± 0.442.63 ± 0.26§**
HDL cholesterol (mmol/l)1.22 ± 0.131.28 ± 0.131.32 ± 0.111.29 ± 0.11
Triacylglycerols (mmol/l)1.51 ± 0.0.261.32 ± 0.191.24 ± 0.201.21 ± 0.19
FFA (mmol/l)1.30 ± 0.251.47 ± 0.261.21 ± 0.191.02 ± 0.18§**
Apolipoprotein B (g/l)1.04 ± 0.061.05 ± 0.061.07 ± 0.071.01 ± 0.06††§**
Total fat mass (kg)24.9 ± 2.425.5 ± 2.626.3 ± 3.125.5 ± 2.7
Lean mass (kg)65.3 ± 0.963.8 ± 0.963.7 ± 1.163.9 ± 0.9
PAI-1 activity23.4 ± 5.224.6 ± 5.325.6 ± 3.815.8 ± 1.8§**
  • Data are means ± SE (n = 12). LDL was calculated by use of the Friedewald formula.

  • *

    * Results during the 8-h metabolic profile before (baseline data) or after (4-week data) the chronic nutritional periods. During the 8-h metabolic profile, values were taken just before (data in the fasting state, 0 min).

  • Data followed by different superscripts (including * and †) for a row are significantly different at P < 0.05.

  • §

    § Changes during the dietary periods (Δ = baseline data − 4-week data, HGI vs. LGI).

  • **

    ** P < 0.05 by paired Student’s test;

  • P < 0.01, and

  • ††

    †† P < 0.001 by ANOVA.