Table 2—

Adjusted* means (95% CI) for baseline HRV measures (ms) by baseline diabetes, glucose, or insulin status: the ARIC study

SDNNrMSSDR-R interval
Diabetes/glucose status (n = 9,940)
    NFG37.31 (36.88–37.74)28.99 (28.52–29.45)916.99 (913.54–920.43)
    IFG36.80 (36.27–37.33)27.74 (27.17–28.31)887.96 (883.75–892.16)
    Diabetes32.75 (31.71–33.78)23.87 (22.75–24.98)852.69 (844.45–860.94)
Glucose quintile (n = 8,971)§
    I37.66 (36.96–38.36)29.82 (29.07–30.57)927.24 (921.68–932.79)
    II37.30 (36.56–38.04)28.42 (27.63–29.22)915.49 (909.63–921.36)
    III37.08 (36.41–37.75)28.19 (27.47–28.91)905.87 (900.56–911.18)
    IV37.04 (36.32–37.77)27.58 (26.80–28.36)895.04 (889.29–900.79)
    V36.74 (35.81–37.67)27.73 (26.73–28.73)872.18 (864.78–879.58)
Hyperinsulinemia status (n = 8,971)§
    Absent37.71 (37.35–38.08)28.95 (28.56–29.34)914.16 (911.29–917.03)
    Present34.47 (33.57–35.37)25.61 (24.64–26.58)862.95 (855.81–870.10)
Insulin quintile (n = 8,971)§
    I38.91 (38.19–39.63)30.95 (30.17–31.72)944.81 (939.12–950.49)
    II38.43 (37.66–39.19)29.40 (28.58–39.22)924.58 (918.59–930.57)
    III37.07 (36.38–37.77)28.14 (27.39–28.89)908.15 (902.69–913.61)
    IV36.66 (35.92–37.40)27.52 (26.73–28.32)883.10 (877.28–888.91)
    V34.12 (33.21–35.03)25.11 (24.13–26.09)853.91 (846.75–861.08)
  • *

    * Adjusted for age, sex, race, study center, hypertension, smoking, education, and BMI.

  • P < 0.05 compared with IFG.

  • P < 0.05 compared with NFG.

  • §

    § Among nondiabetic subjects only. Hyperinsulinemia is defined as fasting insulin ≥115 pmol/l (the 80th percentile).

  • P < 0.05 compared with the lowest quintile (I) of glucose or insulin.

  • P < 0.05 compared with no hyperinsulinemia. Lower cut points for the glucose quintiles: 5.0, 5.3, 5.6, and 6.0 mmol/l. Lower cut points for the insulin quintiles: 43, 57, 79, and 115 pmol/l.