Table 1—

Clinical and biochemical characteristics of the study population

All subjectsTestosterone <9.7 nmol/lTestosterone ≥9.7 nmol/lP
n601050
Age (years)60 ± 157 ± 3.561 ± 1NS
NGT (n)27126
IGT (n)1239
Type 2 diabetes (n)21615
Body composition
    BMI (kg/m2)27 ± 0.632 ± 226 ± 0.50.0004
    WHR0.96 ± 0.011.02 ± 0.050.95 ± 0.010.008
    Body fat (%)24.0 ± 0.9730.1 ± 2.823 ± 0.970.008
Biochemical characteristics
    Testosterone (nmol/l)16 ± 0.86.8 ± 0.517 ± 0.6<0.0001
    SHBG (nmol/l)36 ± 220 ± 339 ± 20.0008
    Fasting glucose (mmol/l)5.9 ± 0.27.5 ± 0.65.6 ± 0.30.017
    Fasting insulin (pmol/l)66 ± 497 ± 360 ± 40.04
    Cholesterol (mmol/l)5.3 ± 0.145.9 ± 0.45.2 ± 0.1NS
    Triglycerides (mmol/l)1.4 ± 0.12.3 ± 0.51.3 ± 0.10.01
    HDL cholesterol (mmol/l)1.3 ± 0.051.0 ± 0.81.32 ± 0.05NS
    Free fatty acids (μmol/l)509 ± 24516 ± 68507 ± 25NS
Glucose clamp data
    Insulin sensitivity (mg ·     kg−1 · min−1)6.5 ± 0.43.6 ± 0.67.3 ± 30.0007
  • Data are means ± SE. P values represent differences between subjects with testosterone levels <9.7 vs. ≥9.7 nmol/l.