Table 5—

Clinical characteristics according to the quartiles of plasma RBP4 concentrations

First quartileSecond quartileThird quartileFourth quartileP for trend
n38 (100)39 (100)38 (100)39 (100)
Plasma RBP4 (μg/ml)13.4 (9.3–15.8)17.7 (15.9–19.4)21.1 (19.5–22.5)26.6 (22.6–48.5)<0.001
NGT (%)22 (57.9)14 (35.9)13 (34.2)8 (20.5)
IGT (%)11 (28.9)13 (33.3)10 (26.3)14 (35.9)<0.001
Type 2 diabetes (%)5 (13.2)12 (30.8)15 (39.5)17 (43.6)
Sex (M/F)10/2812/2716/2222/170.004
Age (years)51 ± 1253 ± 1157 ± 1053 ± 100.055
SBP (mmHg)123 ± 19127 ± 15127 ± 15130 ± 170.313
DBP (mmHg)78 ± 1279 ± 1080 ± 1182 ± 130.304
BMI (kg/m2)24.2 ± 3.724.6 ± 2.924.9 ± 3.225.5 ± 2.30.304
Waist (cm)81 ± 984 ± 887 ± 887 ± 60.005
Fat mass (kg)17.4 ± 6.518.3 ± 4.518.0 ± 5.318.3 ± 3.70.847
Percent body fat27.7 ± 7.929.0 ± 5.527.8 ± 6.427.1 ± 5.50.653
FPG (mmol/l)4.8 ± 1.05.1 ± 1.15.5 ± 1.36.1 ± 1.1<0.001
2-h postchallenge plasma glucose (mmol/l)7.8 ± 3.09.8 ± 4.010.2 ± 4.011.0 ± 3.90.003
Fasting plasma insulin (pmol/l)63 ± 3771 ± 2572 ± 2775 ± 300.331
Triglycerides (mmol/l)*1.40 (0.45–4.00)1.11 (0.44–6.60)1.41 (0.71–8.38)1.70 (0.43–5.86)0.005
Total cholesterol (mmol/l)4.96 ± 0.804.95 ± 1.005.20 ± 0.725.42 ± 1.060.074
LDL cholesterol (mmol/l)3.06 ± 0.802.96 ± 0.723.17 ± 0.713.28 ± 0.930.340
HDL cholesterol (mmol/l)*1.24 (0.73–2.18)1.24 (0.85–1.99)1.18 (0.75–1.99)1.15 (0.83–2.67)0.905
A1C (%)*5.8 (5.2–7.6)5.8 (5.1–8.1)6.2 (5.2–8.1)6.3 (4.6–8.4)0.050
HOMA-IR*1.9 (0.2–8.8)2.5 (0.6–5.4)2.6 (0.9–7.5)3.0 (1.1–14.0)<0.001
HOMA-B*149 (44–661)126 (24–874)135 (31–769)92 (47–356)0.063
  • Data are n (%) or median (range).

  • *

    * These variables were log transformed before analyses.