Control | GDM | Type 2 diabetes | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin | 32–33 split proinsulin | Proinsulin | Insulin | 32–33 split proinsulin | Proinsulin | Insulin | 32–33 split proinsulin | Proinsulin | |||||||
Z weight | 0.36 | 0.43 | 0.38 | 0.48 | 0.48 | 0.46 | 0.40 | 0.43 | 0.34 | ||||||
Leptin | 0.49 | 0.61 | 0.40 | 0.53 | 0.59 | 0.50 | 0.46 | 0.68* | 0.59 | ||||||
Cord glucose | 0.08 | 0.12 | −0.04 | 0.27 | 0.17* | 0.17 | 0.42 | 0.16* | 0.06* |
Spearman’s correlation coefficients of insulin and insulin propeptides to variables from mother and child in offspring of control subjects (n = 86) and mothers with GDM (n = 134) or type 2 diabetes (n = 39). Where the P value for simple Spearman’s correlation is <0.01, r value is shown in bold type; where 0.01 < P < 0.05, r is in standard type; where P > 0.05, r is in italics. For relationships with Z weight, leptin, and cord glucose,
↵* r value for proinsulin or 32–33 split proinsulin significantly different from that of insulin at significance level P < 0.05.