Table 1

Mean (SE) and frequency (%) of baseline characteristics stratified across quartiles of NEFAs, MESA, N = 5,697

CharacteristicQuartiles of NEFAsPtrend
Quartile, n1 (n = 1,380)2 (n = 1,461)3 (n = 1,455)4 (n = 1,401)
NEFA range0.13–0.390.40–0.520.53–0.670.68–2.11
Age, years, mean (SE)58.9 (0.28)60.8 (0.26)62.8 (0.26)64.3 (0.27)<0.001
Sex, % women28.345.361.479.3<0.001
Race, n (%)
 Black370 (26.8)387 (26.5)380 (26.1)324 (23.1)0.11
 Chinese131 (9.5)164 (11.2)204 (14.0)188 (13.4)<0.001
 Hispanic301 (21.8)330 (22.6)298 (20.5)262 (18.7)0.06
 White578 (41.9)580 (39.7)573 (39.4)627 (44.8)0.007
Education, n (%)
 Less than HS233 (16.9)247 (16.9)246 (16.9)212 (15.1)0.46
 HS graduate237 (17.2)251 (17.2)262 (18.0)269 (19.2)0.53
 Some college381 (27.6)395 (27.0)447 (30.7)403 (28.8)0.16
 College graduate237 (17.2)267 (18.2)247 (17.0)269 (19.2)0.42
 Graduate school292 (21.1)301 (20.6)252 (17.4)248 (17.7)0.03
Current smoking, % (SE)14.8 (0.01)12.4 (0.01)13.2 (0.01)12.0 (0.01)0.17
Current alcohol use, % (SE)42.5 (0.01)43.9 (0.01)41.0 (0.01)41.1 (0.01)0.31
BMI, kg/m227.0 (0.14)27.9 (0.13)28.4 (0.13)28.6 (0.14)<0.001
Waist circumference, cm94.5 (0.38)97.1 (0.35)97.69 (0.35)98.8 (0.37)<0.001
hs-CRP, mg/L3.08 (0.16)3.79 (0.15)3.77 (0.15)4.01 (0.16)<0.001
Glucose, mg/dL88.0 (0.28)89.2 (0.26)89.8 (0.26)91.4 (0.28)<0.001
Insulin, mU/L8.5 (0.15)9.5 (0.14)9.7 (0.14)10.3 (0.15)<0.001
n-3, % of total*5.79 (0.06)5.59 (0.05)5.61 (0.05)5.58 (0.06)0.03
EPA, % of total0.99 (0.02)0.88 (0.02)0.87 (0.02)0.86 (0.02)<0.001
DHA, % of total3.86 (0.04)3.79 (0.03)3.80 (0.03)3.80 (0.04)0.56
  • Adjusted for age, sex, race, education, and field center.

  • n-3 FAs = EPA + DHA.

  • *Low n-3 FA category <75th percentile; high n-3 FA category ≥75th percentile. HS, high school.