Table 2

Association of glucose tolerance status with peripheral neuropathy and nerve dysfunction in the PROMISE cohort

MNSI score**VPT**
β (95% CI)P valueβ (95% CI)P value
Prediabetes vs. NFG/NGT (cross-sectional at 3-year follow-up)
 Unadjusted0.38 (0.11, 0.65)0.0050.20 (0.076, 0.32)0.001
 Multivariable adjusted*0.34 (0.075, 0.61)0.010.14 (0.044, 0.24)0.004
Progression of glucose intolerance vs. sustained NFG/NGT
 Unadjusted0.40 (0.14, 0.67)0.0030.20 (0.085, 0.32)0.001
 Multivariable adjusted*0.37 (0.10, 0.63)0.0070.15 (0.052, 0.25)0.002
  • NFG, normal fasting glucose; NGT, normal glucose tolerance.

  • *Adjusted for age, sex, ethnicity, and height.

  • **MNSI scores (with a total score of 10) and VPTs were modeled as continuous variables.