Table 1

Baseline population characteristics by METs

Patients without diagnosed diabetes at baseline
Overall (n = 46,979)<6 METs (n = 5,158)6–9 METs (n = 11,588)10–11 METs (n = 17,876)≥12 METs (n = 12,357)P across METs*
Age, years, mean (SD)52.5 (12.6)64.5 (12.6)57.5 (11.9)50.9 (10.7)45.1 (10.1)<0.001
Female, %48.467.065.650.321.9<0.001
Race, %
 White66.559.961.766.673.5<0.001
 Black26.636.132.726.017.7<0.001
 Other7.04.05.67.48.8<0.001
History of hypertension, %56.579.068.153.840.1<0.001
History of hyperlipidemia, %40.139.343.641.036.1<0.001
History of obesity, %20.322.429.521.98.4<0.001
Family history of coronary heart disease, %52.246.052.153.653.0<0.001
Current smoking status, %41.742.943.643.037.4<0.001
Regular exercise (yes or no), %27.729.735.329.716.7<0.001
Hypertension medication use, %37.761.250.034.620.8<0.001
ACE inhibitor use, %12.119.215.911.27.0<0.001
ARB use, %1.92.42.51.90.9<0.001
β-Blocker use, %15.423.420.214.58.9<0.001
Diuretic use, %16.229.923.914.26.2<0.001
Lipid-lowering medication use, %16.118.320.416.211.2<0.001
Statin use, %14.716.818.914.79.8<0.001
Pulmonary disease medication use, %8.613.210.18.25.9<0.001
Depression medication use, %7.68.19.18.35.0<0.001
Reason for stress test, %
 Chest pain52.145.352.654.451.3<0.001
 Shortness of breath8.811.79.07.98.9<0.001
 “Rule out” ischemia10.610.810.510.710.60.943
 Other28.432.228.027.029.30.009
Peak METs achieved, mean (SD)9.5 (3.0)4.2 (1.2)7.0 (0.2)10.0 (0.0)13.2 (0.8)
  • *P values for trends across METs determined via linear and logistic regression.