Table 2

Most frequently reported adverse events

Once weekly
Once every 2 weeks
Placebo5 mg10 mg20 mg10 mg20 mg
n49*50*49*50*50*49*
Nausea3 (6)11 (22)12 (24)26 (52)16 (32)20 (10)
Diarrhea4 (8)4 (8)5 (10)5 (10)8 (16)9 (18)
Vomiting2 (4)2 (4)2 (4)11 (22)6 (12)12 (24)
Headache3 (6)1 (2)3 (6)6 (12)7 (14)6 (12)
Decreased appetite5 (10)3 (6)4 (8)3 (6)
Dyspepsia4 (8)6 (12)3 (6)2 (4)
Abdominal distension2 (4)2 (4)3 (6)6 (12)
  • Data are n (%).

  • *All patients who received at least one dose of study drug treatment (n = 297) were included in the safety database.