Table 2

Changes in metabolic variables, fitness, and hs-CRP at 1 year

Variable*ILIDSEP value
n922836
Δ Weight (kg)−9.0 ± 7.6−0.8 ± 5.0<0.001
Δ BMI (kg/m2)−3.2 ± 2.6−0.3 ± 1.8<0.001
Δ Waist circumference (cm)−7.4 ± 7.8−0.9 ± 6.3<0.001
Δ Fasting glucose (mg/dl)−21.7 ± 44.4−6.7 ± 46.8<0.001
Δ A1C (%)−0.7 ± 1.0−0.2 ± 0.9<0.001
Δ LDL cholesterol (mg/dl)−4.3 ± 26.2−4.8 ± 28.70.75
Δ Triglycerides (mg/dl)−32.3 ± 114.8−12.6 ± 94.2<0.001
Δ HDL cholesterol (mg/dl)3.2 ± 6.91.4 ± 6.6<0.001
Δ Fitness (submaximal) (MET)1.0 ± 1.40.3 ± 1.1<0.001
hs-CRP in overall group
    1 year (mg/l)2.4 (1.0 to 5.6)3.5 (1.7 to 7.4)
    Δ (%)−43.6−16.7
    Δ (mg/l)−1.24 (−3.4 to −0.1)−0.35 (−2.0 to 0.8)<0.001
hs-CRP in men
    1 year (mg/l)1.4 (0.8 to 2.9)2.2 (1.2 to 4.0)
    Δ (%)−40.5−8.3
    Δ (mg/l)−0.68 (−1.8 to 0.1)−0.11 (−1.2 to 0.7)<0.001
hs-CRP in women
    1 year (mg/l)3.3 (1.6 to 7.8)5.0 (2.6 to 10.0)
    Δ (%)−47.4−20.2
    Δ (mg/l)−1.75 (−4.7 to −0.3)−0.58 (−2.8 to 0.8)<0.001
  • Data are means ± SD or median (IQR) unless otherwise indicated.

  • *Change (Δ) from baseline to 1 year.

  • †For difference between ILI and DSE for change in variable from baseline to 1 year.