Table 2

Dose-response relationship between periodontal attachment loss and IFG and diabetes

HyperglycemiaQuintile (1–5) for attachment loss (reference: quintile 1, n = 2,412)P for trend
Quintile 2 (n = 2,493)Quintile 3 (n = 2,465)Quintile 4 (n = 2,431)Quintile 5 (n = 2,453)
OR (95% CI)OR (95% CI)OR (95% CI)OR (95% CI)
Median attachment loss (quintile 1: 0.19)0.540.931.442.71
IFG*
 Adjusted for age and sex1.10 (0.81–1.49)1.51 (1.14–1.99)1.63 (1.21–2.20)1.70 (1.31–2.21)<0.01
 Additionally adjusted for education, income, and race1.09 (0.80–1.49)1.46 (1.09–1.96)1.56 (1.13–2.14)1.63 (1.24–2.16)<0.01
 Additionally adjusted for smoking, alcohol intake, missing teeth, and dental visit1.06 (0.77–1.47)1.44 (1.07–1.93)1.59 (1.13–2.23)1.65 (1.24–2.21)<0.01
 Additionally adjusted for BMI, central adiposity, and physical activity0.97 (0.69–1.35)1.34 (1.00–1.78)1.54 (1.08–2.18)1.55 (1.16–2.07)<0.01
Diabetes†
 Adjusted for age and sex1.93 (1.17–3.18)2.53 (1.38–4.64)4.33 (2.34–8.02)6.16 (3.54–10.73)<0.01
 Additionally adjusted for education, income, and race2.11 (1.28–3.48)2.70 (1.49–4.91)4.76 (2.50–9.08)5.89 (3.24–10.72)<0.01
 Additionally adjusted for smoking, alcohol intake, missing teeth, and dental visit2.00 (1.21–3.32)2.55 (1.40–4.62)3.84 (2.36–6.24)5.30 (3.01–9.31)<0.01
 Additionally adjusted for BMI, central adiposity, and physical activity1.77 (1.04–3.03)2.21 (1.17–4.17)3.38 (2.06–5.54)4.77 (2.69–8.46)<0.01
  • *Excluding subjects with diabetes. †Excluding subjects with IFG.