Abnormal at baseline | Abnormal after 12 months of SU | Change from baseline to 12 months | Median difference (range) (M0/M12) for score^{*} | |
---|---|---|---|---|

Tone | ||||

Tone (score <7) | 9 (90) | 9 (90) | Improved n = 7 | 1 (0–4), P = 0.016 |

Stable n = 2 | ||||

Still normal n = 1 | ||||

Limb and standing tone | 7 (70) | 5 (50) | Improved n = 3 | −1 (−1 to 0), P = 0.25 |

Stable n = 4 | ||||

Still normal n = 3 | ||||

Laterality | ||||

Laterality score (score <4) | 9 (90) | 2 (20) | Improved n = 8 | 1.5 (0–3), P = 0.008 |

Stable n = 1 | ||||

Still normal n = 1 | ||||

Gesture conception: intending a motor action | ||||

Executive function (PA <10% of CA) | 4 (0) | 5 (40) | Improved n = 0 | 0.02 (−29 to 35), P = 0.57 |

Stable n = 4 | ||||

Still normal n = 5 | ||||

Degraded n = 1 | ||||

Gesture conception: sensory integration | ||||

Auditory attention (score <4) | 7 (70) | 6 (60) | Improved n = 4 | 0 (0–2), P = 0.13 |

Stable n = 3 | ||||

Still normal n = 3 | ||||

Visual attention (score <34) | 9 (90) | 7 (70) | Improved n = 8 | 4 (0–20), P = 0.008 |

Stable n = 1 | ||||

Still normal n = 1 | ||||

Digital perception (score <3) | 5 (50) | 4 (40) | Improved n = 1 | 0 (0–1), P = 1 |

Stable n = 4 | ||||

Still normal n = 4 | ||||

Gesture conception and realization: building the motor program and executing the movement | ||||

Dynamic motor skills (score <7) | 9 (90) | 7 (70) | Improved n = 3 | 0 (−3 to 5), P = 0.50 |

Stable n = 6 | ||||

Still normal n = 1 | ||||

Static motor skills (score <3) | 4 (40) | 4 (40) | Improved n = 1 | 0 (0–1), P = 1 |

Stable n = 3 | ||||

Still normal n = 6 | ||||

General praxia (score <4) | 9 (90) | 7 (70) | Improved n = 4 | 0 (0–3), P = 0.13 |

Stable n = 5 | ||||

Still normal n = 1 | ||||

Two-handed praxia (score <5) | 8 (80) | 8 (80) | Improved n = 4 | 0 (0–2), P = 0.13 |

Stable n = 4 | ||||

Still normal n = 2 | ||||

Gesture imitation (score <5) | 8 (80) | 7 (70) | Improved n = 5 | 0.5 (0–2), P = 0.06 |

Stable n = 3 | ||||

Still normal n = 2 | ||||

Body spatial integration (score <4) | 8 (80) | 8 (80) | Improved n = 5 | 0.5 (0–2), P = 0.06 |

Stable n = 3 | ||||

Still normal n = 2 | ||||

Visual-motor integration (score <13 or 17–19) | 10 (100) | 10 (100) | Improved n = 1 | 0 (0–4), P = 0.50 |

Stable n = 9 | ||||

Visual-spatial construction | 9 (90) | 9 (90) | Improved n = 3 | 15 (0–50), P = 0.06 |

Stable n = 6 | ||||

Still normal n = 1 |

Data are

*n*(%) unless otherwise indicated. CA, chronological age; M0, baseline (just before starting SU therapy); M12, 12 months after starting SU therapy; PA, performance age.↵*Paired Wilcoxon test on continuous scores.