Table 3

Assessment using NP-MOT at baseline and then 12 months after starting SU therapy in 10 patients aged 4–18 years (patient nos. 9–18)

Abnormal at baseline Abnormal after 12 months of SUChange from baseline to 12 monthsMedian difference (range) (M0/M12) for score*
Tone
 Tone (score <7)9 (90)9 (90)Improved n = 71 (0–4), P = 0.016
Stable n = 2
Still normal n = 1
 Limb and standing tone7 (70)5 (50)Improved n = 3−1 (−1 to 0), P = 0.25
Stable n = 4
Still normal n = 3
Laterality
 Laterality score (score <4)9 (90)2 (20)Improved n = 81.5 (0–3), P = 0.008
Stable n = 1
Still normal n = 1
Gesture conception: intending a motor action
 Executive function (PA <10% of CA)4 (0)5 (40)Improved n = 00.02 (−29 to 35), P = 0.57
Stable n = 4
Still normal n = 5
Degraded n = 1
Gesture conception: sensory integration
 Auditory attention (score <4)7 (70)6 (60)Improved n = 40 (0–2), P = 0.13
Stable n = 3
Still normal n = 3
 Visual attention (score <34)9 (90)7 (70)Improved n = 84 (0–20), P = 0.008
Stable n = 1
Still normal n = 1
 Digital perception (score <3)5 (50)4 (40)Improved n = 10 (0–1), P = 1
Stable n = 4
Still normal n = 4
Gesture conception and realization: building the motor program and executing the movement
 Dynamic motor skills (score <7)9 (90)7 (70)Improved n = 30 (−3 to 5), P = 0.50
Stable n = 6
Still normal n = 1
 Static motor skills (score <3)4 (40)4 (40)Improved n = 10 (0–1), P = 1
Stable n = 3
Still normal n = 6
 General praxia (score <4)9 (90)7 (70)Improved n = 40 (0–3), P = 0.13
Stable n = 5
Still normal n = 1
 Two-handed praxia (score <5)8 (80)8 (80)Improved n = 40 (0–2), P = 0.13
Stable n = 4
Still normal n = 2
 Gesture imitation (score <5)8 (80)7 (70)Improved n = 50.5 (0–2), P = 0.06
Stable n = 3
Still normal n = 2
 Body spatial integration (score <4)8 (80)8 (80)Improved n = 50.5 (0–2), P = 0.06
Stable n = 3
Still normal n = 2
 Visual-motor integration (score <13 or 17–19)10 (100)10 (100)Improved n = 10 (0–4), P = 0.50
Stable n = 9
 Visual-spatial construction9 (90)9 (90)Improved n = 315 (0–50), P = 0.06
Stable n = 6
Still normal n = 1
  • Data are n (%) unless otherwise indicated. CA, chronological age; M0, baseline (just before starting SU therapy); M12, 12 months after starting SU therapy; PA, performance age.

  • *Paired Wilcoxon test on continuous scores.