Table 15

Plasma blood glucose and A1C goals for type 1 diabetes by age-group

Values by age (years)Plasma blood glucose goal range (mg/dL)A1CRationale
Before mealsBedtime/overnight
Toddlers and preschoolers (0–6)100–180110–200<8.5%• Vulnerability to hypoglycemia
• Insulin sensitivity
• Unpredictability in dietary intake and physical activity
• A lower goal (<8.0%) is reasonable if it can be achieved without excessive hypoglycemia
School age (612)90–180100–180<8%• Vulnerability of hypoglycemia
• A lower goal (<7.5%) is reasonable if it can be achieved without excessive hypoglycemia
Adolescents and young adults (1319)90–13090–150<7.5%• A lower goal (<7.0%) is reasonable if it can be achieved without excessive hypoglycemia
Key concepts in setting glycemic goals:
• Goals should be individualized and lower goals may be reasonable based on benefit-risk assessment.
• Blood glucose goals should be modified in children with frequent hypoglycemia or hypoglycemia unawareness.
• Postprandial blood glucose values should be measured when there is a discrepancy between preprandial blood glucose values and A1C levels and to help assess glycemia in those on basal/bolus regimens.