Table 1

Demographic and cognitive characteristics of the AA-DHS MIND sample

VariableFull sample (n = 268)Aorta CP absent* (n = 58)Aorta CP present (n = 210)P value
nMean (SD) median or %nMean (SD) median or %nMean (SD) median or %
Age (years)26759.8 (9.25) 59.565852.73 (8.57) 52.8120961.76 (8.46) 61.783.5 × 10−10
Time between baseline CT and MIND MRI visits (years)2674.61 (1.78) 4.28584.97 (1.98) 4.772094.52 (1.71) 4.190.03
Female sex (%)26863.435865.5221062.860.71
African ancestry2650.81 (0.1) 0.82560.81 (0.1) 0.822090.81 (0.1) 0.830.92
BMI (kg/m2)26834.85 (8.21) 33.845837.72 (8.43) 35.9321034.06 (7.99) 32.994.3 × 10−3
Systolic blood pressure (mmHg)268131.9 (18.08) 13158126.76 (14.95) 125210133.31 (18.64) 1330.02
Diastolic blood pressure (mmHg)26876.08 (10.7) 75.755878.22 (10.54) 8021075.5 (10.7) 74.250.04
Prior coronary artery bypass graft (%)2683.425802104.370.09
Hypertension (%)26788.015881.0320989.950.06
Smoking history (pack-years)2619.55 (14.68) 1.3583.2 (7.82) 020311.36 (15.67) 38.4 × 10−6
Current or past smoker (%)26749.065822.4120956.464.7 × 10−6
Oral diabetes medication (%)26879.855884.4821078.570.32
Insulin diabetes medication (%)26838.435836.2121039.050.70
Statin therapy (%)26650.385735.0920954.559.4 × 10−3
ACE/ARB therapy (%)26851.875844.8321053.810.22
Diabetes duration (years)26714.48 (7.57) 12.815812.93 (6.03) 11.0720914.91 (7.9) 13.240.09
Education level1.6 × 10−4
 High school education (%)26827.995820.6921030
 Some college or a college diploma (%)26843.285843.121043.33
 Graduate school education (%)26817.915834.4821013.33
3MS, range 0–10026886.05 (8.62) 875888.52 (8.29) 9121085.37 (8.6) 875.0 × 10−5
MoCA, range 0–3026819.47 (4.01) 205820.6 (4.68) 2121019.16 (3.75) 200.01
  • ARB, angiotensin receptor blocker.

  • *Reflects Aorta CP mass score 0.