Table 1

Anthropometric and metabolic data before and at 8 weeks after surgery in the group with T2DM and the NGT group

T2DM before surgeryT2DM after surgeryPNGT before surgeryNGT after surgeryP
Weight (kg)121.1 ± 3.0104.5 ± 2.7<0.001114.5 ± 5.099.7 ± 4.6<0.001
BMI (kg/m2)42.7 ± 0.736.9 ± 0.7<0.00141.3 ± 1.036.4 ± 0.8<0.001
Fat mass (kg)56.6 ± 2.443.0 ± 2.4<0.00156.7 ± 3.345.4 ± 2.3<0.001
Waist-to-hip ratio0.97 ± 0.020.94 ± 0.020.0060.90 ± 0.03*0.87 ± 0.03#0.066
Plasma glucose
 Fasting (mmol/L)9.2 ± 0.86.2 ± 0.3<0.0015.2 ± 0.14.9 ± 0.10.089
 2 h (mmol/L)9.4 ± 0.86.4 ± 0.3<0.0015.4 ± 0.2*5.0 ± 0.0#0.022
Serum insulin
 Fasting (mU/L)15.3 (4.3–61.2)11.3 (2.9–27.0)<0.00111.0 ± 1.66.7 ± 0.7#0.008
 2 h (mU/L)18.4 (5.2–78.9)11.2 (4.9–31.0)0.00112.4 (4.4–63.5)*6.0 (5.0–7.4)#0.042
Fasting
 Glucagon (ng/L)74.6 ± 9.858.0 ± 8.30.00149.4 ± 5.048.1 ± 5.00.865
 Free fatty acid (mmol/L)0.85 ± 0.080.77 ± 0.050.2070.72 ± 0.090.80 ± 0.070.263
 Triacylglycerol (mmol/L)1.5 (0.6–3.7)1.1 (0.5–2.2)0.0111.2 ± 0.21.1 ± 0.20.16
 ALT (units/L)37.7 ± 4.125.7 ± 2.40.00924.3 ± 2.822.1 ± 3.70.542
 GGT (units/L)33 (13–148)15 (7–69)0.00223 (8–39)11 (5–122)0.234
  • *Indicates a statistically significant difference between the two groups at baseline.

  • #Indicates a statistically significant difference between the two groups at week 8.