Table 2

Results of logistic regression model for metformin intolerance

OR (95% CI)P
Age1.11 (1.08–1.13)<0.001
Sex (females vs. males)1.82 (1.26–2.65)0.002
Weight0.99 (0.97–1.00)0.031
Use of OCT1-inhibiting drugs1.75 (1.22–2.49)0.002
Two reduced-function OCT1 alleles2.27 (1.31–3.92)0.003
Number of SERT S* alleles1.31 (1.02–1.67)0.031
  • Logistic regression analysis included 164 intolerant and 1,356 tolerant patients.