Table 3

Results of Cox proportional hazards regression analysis of variables for prediction of major amputation

Variables at baselineHR95% CIP value*
Univariate analysis
 DM1.871.12–3.120.017
Multivariate analysis
 Age1.010.99–1.030.29
 DM1.590.91–2.780.11
 Stroke0.880.45–1.700.70
 Coronary disease1.020.59–1.750.95
 PAD1.470.73–2.950.28
 Former smoker0.910.45–1.810.78
 Current smoker1.390.65–2.980.40
 eGFR <30 mL/min/1.73 m21.590.81–3.130.18
 Rutherford category2.031.28–3.210.003
 ABI <0.71.260.68–2.320.46
 ABI >1.42.621.23–5.570.012
Multivariate analysis, best performing model
 DM1.560.92–2.650.10
 Rutherford category1.951.24–3.060.004
 ABI <0.71.320.73–2.410.36
 ABI >1.42.781.37–5.640.005
  • *Stratified by randomization.