Table 1

Classification for diabetic neuropathies

Diabetic neuropathies
A. Diffuse neuropathy
  DSPN
   • Primarily small-fiber neuropathy
   • Primarily large-fiber neuropathy
   • Mixed small- and large-fiber neuropathy (most common)
  Autonomic
   Cardiovascular
    • Reduced HRV
    • Resting tachycardia
    • Orthostatic hypotension
    • Sudden death (malignant arrhythmia)
   Gastrointestinal
    • Diabetic gastroparesis (gastropathy)
    • Diabetic enteropathy (diarrhea)
    • Colonic hypomotility (constipation)
   Urogenital
    • Diabetic cystopathy (neurogenic bladder)
    • Erectile dysfunction
    • Female sexual dysfunction
   Sudomotor dysfunction
    • Distal hypohydrosis/anhidrosis,
    • Gustatory sweating
   Hypoglycemia unawareness
   Abnormal pupillary function
B. Mononeuropathy (mononeuritis multiplex) (atypical forms)
  Isolated cranial or peripheral nerve (e.g., CN III, ulnar, median, femoral, peroneal)
  Mononeuritis multiplex (if confluent may resemble polyneuropathy)
C. Radiculopathy or polyradiculopathy (atypical forms)
  Radiculoplexus neuropathy (a.k.a. lumbosacral polyradiculopathy, proximal motor amyotrophy)
  Thoracic radiculopathy
Nondiabetic neuropathies common in diabetes
 Pressure palsies
 Chronic inflammatory demyelinating polyneuropathy
 Radiculoplexus neuropathy
 Acute painful small-fiber neuropathies (treatment-induced)