Table 1

Baseline characteristics of 3,216 subjects without known CHD and ischemic stroke at SHS baseline, by TG and HDL-C status

Total population (n = 3,216)TG and HDL-C status* (n = 3,216)
High TG, low HDL-CHigh TG, normal HDL-CNormal TG, low HDL-CNormal TG, normal HDL-CP value
Sample size, n (%)775 (24)288 (9)975 (30)1,178 (37)
TG (mg/dL), median (IQR),118 (82, 170)215 (175, 284)187 (163, 221)103 (80, 124)85 (64, 113)<0.001a
HDL-C (mg/dL), median (IQR)
 Men41 (34, 49)32 (28, 35)45 (42, 49)35 (32, 37)49 (43, 57)<0.001a
 Women46 (40, 56)39 (34, 43)58 (52, 63)42 (38, 46)58 (53, 67)<0.001a
Age (years), mean (SD)56 (8)56 (8)56 (8)56 (8)56 (8)0.264b
 45–55, n (%)1,617 (50)394 (50)150 (52)500 (51)573 (49)0.881b
 56–65, n (%)1,037 (32)248 (32)92 (32)307 (31)390 (33)
 ≥66, n (%)562 (18)133 (17)46 (16)168 (17)215 (18)
Female, n (%)1,916 (60)495 (64)147 (51)662 (68)612 (52)<0.001b
Diabetes, n (%)1,334 (41)457 (60)116 (41)422 (44)339 (30)<0.001b
Fasting plasma glucose (mg/dL), median (IQR)110 (98, 152)128 (106, 232)113 (100, 169)111 (99, 155)104 (95, 121)<0.001a
Fasting insulin (μU/mL), median (IQR)15 (9, 24)20 (12, 30)16 (9, 24)16 (11, 26)11 (6, 18)<0.001a
BMI (kg/m2), mean (SD)30 (6)31 (5)30 (5)32 (6)29 (6)<0.001b
Waist circumference (cm), mean (SD)
 Men102 (13)106 (11)103 (11)105 (14)99 (13)<0.001b
 Women105 (15)107 (12)103 (13)107 (15)101 (16)<0.001b
Total physical activity (MET-h/week), median (IQR)**
 Men78 (20, 159)83 (19, 173)106 (39,187)61 (13, 153)77 (22, 149)0.060a
 Women45 (10, 105)48 (8, 102)59 (13, 106)37 (10, 106)46 (11, 106)0.073a
Smoking, n (%)0.037b
 Current1,239 (39)327 (42)96 (33)355 (36)461 (39)0.021b
 Past1,040 (32)249 (32)101 (35)309 (32)381 (32)0.760b
 Never935 (29)199 (26)91 (32)311 (32)334 (28)
LDL-C (mg/dL), median (IQR)119 (98, 141)123 (102, 146)122 (99, 148)118 (97, 138)117 (96, 138)<0.001a
Hypertension, n (%)***1143 (36)315 (41)133 (46)320 (33)375 (32)<0.001b
Antihypertensive medication, n (%)562 (17)177 (17)62 (17)162 (13)161 (11)<0.001a
Blood pressure (mmHg), median (IQR)
 SBP124 (113, 136)125 (115, 137)129 (118, 141)122 (111, 134)124 (113, 135)<0.001a
 DBP76 (70, 83)77 (70, 83)79 (72, 86)75 (69, 82)76 (69, 82)<0.001a
Microalbuminuria, n (%)#507 (16)158 (21)54 (19)153 (16)142 (12)<0.001b
Macroalbuminuria, n (%)#237 (7)97 (13)36 (13)48 (5)56 (5)<0.001b
eGFR-MDRD (mL/min), mean (SD)82 (23)83 (33)82 (22)80 (18)82 (18)0.277b
  • DBP, diastolic blood pressure; IQR, interquartile range; SBP, systolic blood pressure.

  • *High TG means TG levels ≥150 mg/dL; low HDL-C means HDL-C levels <40 mg/dL (men) or 50 mg/dL (women).

  • **Total physical activity included leisure time and occupational physical activities over the past year and was presented in MET-h/week to capture all energy expenditure in all activities (30).

  • ***Hypertension: SBP ≥140 mmHg, DBP ≥90 mmHg, or receiving antihypertensive medication.

  • #Microalbuminuria and macroalbuminuria: UACR ≥30 mg/g but <300 mg/g and creatinine ratio ≥300 mg/g, respectively.

  • aP values: χ2 test (categorical variables) or ANOVA test (for continuous variables with normal distribution).

  • bP value for nonparametric median scores test.