Table 2

Multivariable multinomial logistic regression model investigating factors associated with AAb status and type 1 diabetes

Single AAb+Multiple AAb+Type 1 diabetes
Reference group and characteristicRRR (95% CI)P valueRRR (95% CI)P valueRRR (95% CI)P value
AAb
 Log trypsinogen level (ng/mL)1.98 (0.76, 5.14)0.160.29 (0.09, 0.88)<0.050.10 (0.04, 0.24)<0.0001
 Age (years)0.99 (0.94, 1.04)0.731.02 (0.96, 1.08)0.560.92 (0.88, 0.98)<0.01
 BMI (kg/m2)1.06 (0.99, 1.14)0.080.98 (0.88, 1.08)0.621.05 (0.98, 1.13)0.17
Single AAb+
 Log trypsinogen level (ng/mL)0.08 (0.02, 0.40)<0.010.02 (0.005, 0.11)<0.0001
 Age (years)0.99 (0.93, 1.07)0.870.89 (0.83, 0.96)<0.01
 BMI (kg/m2)0.90 (0.80, 1.02)0.110.97 (0.87, 1.08)0.60
Multiple AAb+
 Log trypsinogen level (ng/mL)0.20 (0.05, 0.79)<0.05
 Age (years)0.89 (0.83, 0.97)<0.01
 BMI (kg/m2)1.07 (0.96, 1.20)0.22
  • Data are presented for single-AAb+ subjects without diabetes, multiple-AAb+ subjects without diabetes, and patients with type 1 diabetes (new-onset and established combined) compared with the reference group. AAb subjects are control and relatives combined.