Table 2

Correlation between gut microbiota composition and serum zonulin and HbA1c levels in children with type 1 diabetes and MODY2

ZonulinHbA1c
Type 1 diabetesMODY2Type 1 diabetesMODY2
Ruminococcus−0.162 (P = 0.55)−0.540 (P = 0.036)Ruminococcus−0.362 (P = 0.18)−0.584 (P = 0.025)
Roseburia−0.320 (P = 0.031)−0.732 (P = 0.48)Firmicutes-to-Bacteroidetes ratio−0.561 (P = 0.029)−0.332 (P = 0.45)
Prevotella0.560 (P = 0.37)0.798 (P = 0.037)Blautia0.559 (P = 0.038)0.740 (P = 0.79)
Faecalibacterium−0.703 (P = 0.027)−0.547 (P = 0.49)Streptococcus0.068 (P = 0.018)0.441 (P = 0.12)
Bacteroides0.739 (P = 0.004)0.350 (P = 0.090)
Veillonella0.570 (P = 0.033)0.704 (P = 0.04)
  • Correlations are reported as Spearman ρ (r), and P values are given in parentheses. Statistical significance was set at a P value of <0.05.