Table 4.3

Assessment of hypoglycemia risk

Factors that increase risk of treatment-associated hypoglycemia
  • • Use of insulin or insulin secretagogues (i.e., sulfonylureas, meglitinides)

  • • Impaired kidney or hepatic function

  • • Longer duration of diabetes

  • • Frailty and older age

  • • Cognitive impairment

  • • Impaired counterregulatory response, hypoglycemia unawareness

  • • Physical or intellectual disability that may impair behavioral response to hypoglycemia

  • • Alcohol use

  • • Polypharmacy (especially ACE inhibitors, angiotensin receptor blockers, nonselective β-blockers)

  • See references 114118.