Table 11.1

CKD stages and corresponding focus of kidney-related care

CKD stageFocus of kidney-related care
StageeGFR (mL/min/1.73 m2)Evidence of kidney damage*Diagnose cause of kidney injuryEvaluate and treat risk factors for CKD progression**Evaluate and treat CKD complications***Prepare for renal replacement therapy
No clinical evidence of CKD≥60
1≥90+
260–89+
330–59+/−
415–29+/−
5<15+/−
  • CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate.

  • CKD stages 1 and 2 are defined by evidence of kidney damage (+), while CKD stages 3–5 are defined by reduced eGFR with or without evidence of kidney damage (+/−). At any stage of CKD, the degree of albuminuria, observed history of eGFR loss, and cause of kidney damage (including possible causes other than diabetes) may also be used to characterize CKD, gauge prognosis, and guide treatment decisions.

  • * Kidney damage is most often manifest as albuminuria (UACR ≥30 mg/g Cr) but can also include glomerular hematuria, other abnormalities of the urinary sediment, radiographic abnormalities, and other presentations.

  • ** Risk factors for CKD progression include elevated blood pressure, hyperglycemia, and albuminuria.

  • *** See Table 11.2.