The Changing "Face" of the Type 2 Diabetes Epidemic
Treatment Options for Type 2 Diabetes in Adolescents and Youth

Recent reports demonstrate an incredibly worrisome finding, specifically that there is an increased frequency of type 2 diabetes in youth. Given the importance of the problem of type 2 diabetes in youth and the need to effectively disseminate the information, our editorial team has elected to feature the TODAY study in this issue of Diabetes Care. Specifically, manuscripts from TODAY featured in this issue provide new data on the efficacy and safety of clinical treatment and longitudinal observation of specific risk factors and complications for the new “faces” for the type 2 diabetes epidemic, namely adolescents.

> Read ADA's News Release on the TODAY Series here.
> Access the listing of the TODAY Study Group here.

Editor's Commentary:
“TODAY” Reflects on the Changing “Faces” of Type 2 Diabetes
William T. Cefalu, MD
Editor in Chief, Diabetes Care

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Original Article:
Rapid Rise in Hypertension and Nephropathy in Youth With Type 2 Diabetes: The TODAY Clinical Trial
TODAY Study Group

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Original Article:
Treatment Effects on Measures of Body Composition in the TODAY Clinical Trial
TODAY Study Group

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Original Article:
Effects of Metformin, Metformin Plus Rosiglitazone, and Metformin Plus Lifestyle on Insulin Sensitivity and b-Cell Function in TODAY
TODAY Study Group

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Original Article:
Lipid and Inflammatory Cardiovascular Risk Worsens Over 3 Years in Youth With Type 2 Diabetes: The TODAY Clinical Trial
TODAY Study Group

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Original Article:
Safety and Tolerability of the Treatment of Youth-Onset Type 2 Diabetes: The TODAY Experience
TODAY Study Group

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Brief Report:
Retinopathy in Youth With Type 2 Diabetes Participating in the TODAY Clinical Trial
TODAY Study Group

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Commentary:
The TODAY Study: An NIH Perspective on Its Implications for Research
Barbara L. Linder, MD, PhD; Judith E. Fradkin, MD; Griffin P. Rodgers, MD

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Commentary:
Crisis in Care: Limited Treatment Options for Type 2 Diabetes in Adolescents and Youth
William V. Tamborlane, MD; Georgeanna Klingensmith, MD

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