Genetics-Type 2 Diabetes

Genetics-Type 2 Diabetes

Open Access
Large-Scale Analyses Provide No Evidence for Gene-Gene Interactions Influencing Type 2 Diabetes Risk
Abhishek Nag, Mark I. McCarthy, Anubha Mahajan

Diabetes Nov 2020, 69 (11) 2518-2522; DOI: 10.2337/db20-0224
Open Access
Epigenetic Changes in Islets of Langerhans Preceding the Onset of Diabetes
Meriem Ouni, Sophie Saussenthaler, Fabian Eichelmann, Markus Jähnert, Mandy Stadion, Clemens Wittenbecher, Tina Rönn, Lisa Zellner, Pascal Gottmann, Charlotte Ling, Matthias B. Schulze, Annette Schürmann

Diabetes Nov 2020, 69 (11) 2503-2517; DOI: 10.2337/db20-0204
Open Access
LDL Cholesterol and Dysglycemia: an Intriguing Physiological Relationship
Jordi Merino, Jerome I. Rotter

Diabetes Oct 2020, 69 (10) 2058-2060; DOI: 10.2337/dbi20-0031
Open Access
Longitudinal Analysis of Serum Cytokine Levels and Gut Microbial Abundance Links IL-17/IL-22 With Clostridia and Insulin Sensitivity in Humans
Xin Zhou, Jethro S. Johnson, Daniel Spakowicz, Wenyu Zhou, Yanjiao Zhou, Erica Sodergren, Michael Snyder, George M. Weinstock

Diabetes Aug 2020, 69 (8) 1833-1842; DOI: 10.2337/db19-0592
Open Access
Homozygous Hypomorphic HNF1A Alleles Are a Novel Cause of Young-Onset Diabetes and Result in Sulfonylurea-Sensitive Diabetes
Shivani Misra, Neelam Hassanali, Amanda J. Bennett, Agata Juszczak, Richard Caswell, Kevin Colclough, Jonathan Valabhji, Sian Ellard, Nicholas S. Oliver, Anna L. Gloyn

Diabetes Care Apr 2020, 43 (4) 909-912; DOI: 10.2337/dc19-1843
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A Mendelian Randomization Study Provides Evidence That Adiposity and Dyslipidemia Lead to Lower Urinary Albumin-to-Creatinine Ratio, a Marker of Microvascular Function
Francesco Casanova, Andrew R. Wood, Hanieh Yaghootkar, Robert N. Beaumont, Samuel E. Jones, Kim M. Gooding, Kunihiko Aizawa, W. David Strain, Andrew T. Hattersley, Faisel Khan, Angela C. Shore, Timothy M. Frayling, Jessica Tyrrell

Diabetes May 2020, 69 (5) 1072-1082; DOI: 10.2337/db19-0862
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Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes
Prapaporn Jungtrakoon, Jun Shirakawa, Patinut Buranasupkajorn, Manoj K. Gupta, Dario F. De Jesus, Marcus G. Pezzolesi, Aussara Panya, Timothy Hastings, Chutima Chanprasert, Christine Mendonca, Rohit N. Kulkarni, Alessandro Doria

Diabetes May 2019, 68 (5) 1084-1093; DOI: 10.2337/db17-0821
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Assessment of MTNR1B Type 2 Diabetes Genetic Risk Modification by Shift Work and Morningness-Eveningness Preference in the UK Biobank
Hassan S. Dashti, Céline Vetter, Jacqueline M. Lane, Matt C. Smith, Andrew R. Wood, Michael N. Weedon, Martin K. Rutter, Marta Garaulet, Frank A.J.L. Scheer, Richa Saxena

Diabetes Feb 2020, 69 (2) 259-266; DOI: 10.2337/db19-0606
Open Access
Clinical and Molecular Prevalence of Lipodystrophy in an Unascertained Large Clinical Care Cohort
Claudia Gonzaga-Jauregui, Wenzhen Ge, Jeffrey Staples, Cristopher Van Hout, Ashish Yadav, Ryan Colonie, Joseph B. Leader, H. Lester Kirchner, Michael F. Murray, Jeffrey G. Reid, David J. Carey, John D. Overton, Alan R. Shuldiner, Omri Gottesman, Steve Gao, Jesper Gromada, Aris Baras, Judith Altarejos

Diabetes Feb 2020, 69 (2) 249-258; DOI: 10.2337/db19-0447
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DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes
Connor A. Emdin, Amit V. Khera, Krishna Aragam, Mary Haas, Mark Chaffin, Derek Klarin, Pradeep Natarajan, Alexander Bick, Seyedeh M. Zekavat, Akihiro Nomura, Diego Ardissino, James G. Wilson, Heribert Schunkert, Ruth McPherson, Hugh Watkins, Roberto Elosua, Matthew J. Bown, Nilesh J. Samani, Usman Baber, Jeanette Erdmann, Namrata Gupta, John Danesh, Danish Saleheen, Stacey Gabriel, Sekar Kathiresan

Diabetes Jan 2019, 68 (1) 226-234; DOI: 10.2337/db18-0857

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