Islet Biology-Signal Transduction

Islet Biology-Signal Transduction

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Loss of Furin in β-Cells Induces an mTORC1-ATF4 Anabolic Pathway That Leads to β-Cell Dysfunction
Bas Brouwers, Ilaria Coppola, Katlijn Vints, Bastian Dislich, Nathalie Jouvet, Leentje Van Lommel, Charlotte Segers, Natalia V. Gounko, Lieven Thorrez, Frans Schuit, Stefan F. Lichtenthaler, Jennifer L. Estall, Jeroen Declercq, Bruno Ramos-Molina, John W.M. Creemers

Diabetes Feb 2021, 70 (2) 492-503; DOI: 10.2337/db20-0474
Open Access
Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia
Nadejda Bozadjieva Kramer, Camila Lubaczeuski, Manuel Blandino-Rosano, Grant Barker, George K. Gittes, Alejandro Caicedo, Ernesto Bernal-Mizrachi

Diabetes Feb 2021, 70 (2) 477-491; DOI: 10.2337/db20-0440
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Deciphering the Complex Communication Networks That Orchestrate Pancreatic Islet Function
Jonathan Weitz, Danusa Menegaz, Alejandro Caicedo

Diabetes Jan 2021, 70 (1) 17-26; DOI: 10.2337/dbi19-0033
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A Computational Approach for Defining a Signature of β-Cell Golgi Stress in Diabetes
Robert N. Bone, Olufunmilola Oyebamiji, Sayali Talware, Sharmila Selvaraj, Preethi Krishnan, Farooq Syed, Huanmei Wu, Carmella Evans-Molina

Diabetes Nov 2020, 69 (11) 2364-2376; DOI: 10.2337/db20-0636
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Pancreatic Pericytes Support β-Cell Function in a Tcf7l2-Dependent Manner
Lina Sakhneny, Eleonor Rachi, Alona Epshtein, Helen C. Guez, Shane Wald-Altman, Michal Lisnyansky, Laura Khalifa-Malka, Adina Hazan, Daria Baer, Avi Priel, Miguel Weil, Limor Landsman

Diabetes Mar 2018, 67 (3) 437-447; DOI: 10.2337/db17-0697
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A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells
Teresa Buenaventura, Nisha Kanda, Phoebe C. Douzenis, Ben Jones, Stephen R. Bloom, Pauline Chabosseau, Ivan R. Corrêa, Domenico Bosco, Lorenzo Piemonti, Piero Marchetti, Paul R. Johnson, A.M. James Shapiro, Guy A. Rutter, Alejandra Tomas

Diabetes Mar 2018, 67 (3) 385-399; DOI: 10.2337/db17-0639
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MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells
Paul Richards, Latif Rachdi, Masaya Oshima, Piero Marchetti, Marco Bugliani, Mathieu Armanet, Catherine Postic, Sandra Guilmeau, Raphael Scharfmann

Diabetes Mar 2018, 67 (3) 461-472; DOI: 10.2337/db17-0595
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Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response
Michelle R. Marasco, Abass M. Conteh, Christopher A. Reissaus, John E. Cupit, Evan M. Appleman, Raghavendra G. Mirmira, Amelia K. Linnemann

Diabetes Aug 2018, 67 (8) 1576-1588; DOI: 10.2337/db17-1280
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Endogenous Fatty Acids Are Essential Signaling Factors of Pancreatic β-Cells and Insulin Secretion
Sebastian Hauke, Kaya Keutler, Prasad Phapale, Dmytro A. Yushchenko, Carsten Schultz

Diabetes Oct 2018, 67 (10) 1986-1998; DOI: 10.2337/db17-1215
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Restoration of Glucose-Stimulated Cdc42-Pak1 Activation and Insulin Secretion by a Selective Epac Activator in Type 2 Diabetic Human Islets
Rajakrishnan Veluthakal, Oleg G. Chepurny, Colin A. Leech, Frank Schwede, George G. Holz, Debbie C. Thurmond

Diabetes Oct 2018, 67 (10) 1999-2011; DOI: 10.2337/db17-1174

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