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Original Articles

The Incidence of Childhood IDDM in New South Wales, Australia

  1. Charles F Verge, MBBS,
  2. Martin Silink, MD and
  3. Neville J Howard, MBBS
  1. Ray Williams Institute for Pediatric Endocrinology, Royal Alexandra Hospital for Children Sydney, Australia
  1. Address correspondence and reprint requests to Charles F. Verge, MBBS, Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Box B140,4200 East 9th Avenue, Denver, CO 80262.
Diabetes Care 1994 Jul; 17(7): 693-696. https://doi.org/10.2337/diacare.17.7.693
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Abstract

OBJECTIVE To determine the incidence of insulin-dependent diabetes mellitus (IDDM) in children 0–14 years of age in the state of New South Wales, Australia, which has a total population of 5.73 million.

RESEARCH DESIGN AND METHODS We established a prospective register, identifying 361 incident cases over a 2-year period (1990–1991) with two independent sources of case ascertainment. The primary source was the reporting of newly diagnosed patients by physicians and diabetes educators. The secondary source was a subsidized syringe scheme.

RESULTS Using the capture-recapture method, ascertainment was estimated to be 99.4% complete. The age-standardized incidence rate was 14.5 per 100,000 person-years (95% confidence interval: 13.0–16.0). No significant differences were found when comparing the first and second years of the register, boys and girls, geographical areas, or Aboriginal and non-Aboriginal children. There was seasonal variation in the onset (with more cases in winter), which was evident in the 10- to 14-year age-group (P = 0.01), but not in younger age-groups. A first-degree relative was already affected in 6.9% of the cases. No significant difference was noted in the age at onset when comparing cases with and without an affected first-degree relative.

CONCLUSIONS The incidence of childhood IDDM in New South Wales is similar to rates found in other predominantly Anglo-Saxon populations. IDDM occurs in Aboriginal children with a frequency comparable to that in the rest of the population.

  • Received November 15, 1993.
  • Accepted January 27, 1994.
  • Copyright © 1994 by the American Diabetes Association

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July 1994, 17(7)
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The Incidence of Childhood IDDM in New South Wales, Australia
Charles F Verge, Martin Silink, Neville J Howard
Diabetes Care Jul 1994, 17 (7) 693-696; DOI: 10.2337/diacare.17.7.693

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The Incidence of Childhood IDDM in New South Wales, Australia
Charles F Verge, Martin Silink, Neville J Howard
Diabetes Care Jul 1994, 17 (7) 693-696; DOI: 10.2337/diacare.17.7.693
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