Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo.

L Heinemann; R Linkeschova; K Rave; B Hompesch; M Sedlak; T Heise

doi:10.2337/diacare.23.5.644

Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo.

L Heinemann,
R Linkeschova,
K Rave,
B Hompesch,
M Sedlak and
T Heise

Department of Metabolic Diseases and Nutrition, the World Health Organization Collaborating Centre for Diabetes, Heinrich-Heine University, Düsseldorf, Germany. lutz.heinemann@profil-research.de

Diabetes Care 2000 May; 23(5): 644-649. https://doi.org/10.2337/diacare.23.5.644

Article Information

vol. 23 no. 5 644-649

DOI

https://doi.org/10.2337/diacare.23.5.644

PubMed

10834424

Published By

American Diabetes Association

Print ISSN

0149-5992

Online ISSN

1935-5548

History

Published in print May 1, 2000.

Author Information

L Heinemann,
R Linkeschova,
K Rave,
B Hompesch,
M Sedlak and
T Heise

Department of Metabolic Diseases and Nutrition, the World Health Organization Collaborating Centre for Diabetes, Heinrich-Heine University, Düsseldorf, Germany. lutz.heinemann@profil-research.de

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Article usage: May 2001 to January 2021

Rendering graph...

	Abstract	Full	Pdf
May 2001	9	0	45
Jun 2001	19	0	100
Jul 2001	7	0	63
Aug 2001	11	0	63
Sep 2001	6	0	45
Oct 2001	8	0	51
Nov 2001	6	0	35
Dec 2001	6	0	41
Jan 2002	9	0	56
Feb 2002	6	0	40
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Apr 2002	7	0	68
May 2002	6	5	54
Jun 2002	4	0	45
Jul 2002	6	0	39
Aug 2002	5	4	51
Sep 2002	6	2	22
Oct 2002	1	6	59
Nov 2002	7	0	59
Dec 2002	4	0	33
Jan 2003	4	2	42
Feb 2003	7	0	56
Mar 2003	2	0	48
Apr 2003	7	0	63
May 2003	16	0	62
Jun 2003	18	0	81
Jul 2003	17	4	51
Aug 2003	6	0	46
Sep 2003	16	0	58
Oct 2003	18	0	75
Nov 2003	24	0	72
Dec 2003	10	0	42
Jan 2004	16	0	67
Feb 2004	10	0	79
Mar 2004	21	0	79
Apr 2004	13	0	65
May 2004	16	0	82
Jun 2004	19	0	53
Jul 2004	15	0	48
Aug 2004	25	0	88
Sep 2004	17	0	53
Oct 2004	39	0	55
Nov 2004	28	0	67
Dec 2004	27	0	30
Jan 2005	28	6	35
Feb 2005	34	0	58
Mar 2005	67	0	40
Apr 2005	35	0	71
May 2005	22	0	43
Jun 2005	30	0	33
Jul 2005	29	0	33
Aug 2005	29	1	40
Sep 2005	42	0	56
Oct 2005	34	0	76
Nov 2005	33	0	62
Dec 2005	26	0	35
Jan 2006	20	0	70
Feb 2006	25	0	73
Mar 2006	28	0	94
Apr 2006	28	0	50
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Jun 2006	34	0	44
Jul 2006	23	0	33
Aug 2006	25	0	61
Sep 2006	33	0	57
Oct 2006	35	0	65
Nov 2006	46	0	54
Dec 2006	33	0	48
Jan 2007	43	0	48
Feb 2007	37	0	37
Mar 2007	43	0	69
Apr 2007	42	0	64
May 2007	40	0	55
Jun 2007	36	0	66
Jul 2007	36	0	60
Aug 2007	45	0	49
Sep 2007	33	0	55
Oct 2007	49	0	125
Nov 2007	41	0	53
Dec 2007	25	0	39
Jan 2008	48	0	61
Feb 2008	44	0	59
Mar 2008	39	0	85
Apr 2008	25	0	58
May 2008	19	0	68
Jun 2008	9	0	68
Jul 2008	20	0	66
Aug 2008	17	0	57
Sep 2008	26	0	79
Oct 2008	23	0	80
Nov 2008	32	0	65
Dec 2008	33	0	67
Jan 2009	22	0	52
Feb 2009	37	0	71
Mar 2009	53	0	92
Apr 2009	39	0	62
May 2009	28	0	37
Jun 2009	44	0	66
Jul 2009	63	0	73
Aug 2009	28	0	34
Sep 2009	39	0	46
Oct 2009	50	0	47
Nov 2009	46	0	28
Dec 2009	35	0	39
Jan 2010	34	0	43
Feb 2010	48	0	88
Mar 2010	38	0	46
Apr 2010	65	0	69
May 2010	48	0	81
Jun 2010	44	0	69
Jul 2010	44	0	48
Aug 2010	60	0	64
Sep 2010	33	0	51
Oct 2010	51	0	73
Nov 2010	59	0	66
Dec 2010	40	0	48
Jan 2011	54	0	60
Feb 2011	62	0	102
Mar 2011	67	0	73
Apr 2011	61	0	93
May 2011	50	0	81
Jun 2011	51	2	64
Jul 2011	44	2	65
Aug 2011	55	2	43
Sep 2011	58	10	69
Oct 2011	66	0	67
Nov 2011	93	1	82
Dec 2011	69	2	82
Jan 2012	56	1	56
Feb 2012	45	0	41
Mar 2012	88	0	84
Apr 2012	85	1	66
May 2012	82	0	62
Jun 2012	65	0	59
Jul 2012	52	0	57
Aug 2012	61	0	80
Sep 2012	69	0	52
Oct 2012	88	0	90
Nov 2012	84	0	79
Dec 2012	59	0	44
Jan 2013	75	0	54
Feb 2013	91	0	59
Mar 2013	77	0	72
Apr 2013	68	1	62
May 2013	83	0	56
Jun 2013	52	0	57
Jul 2013	90	0	70
Aug 2013	63	0	51
Sep 2013	58	0	59
Oct 2013	59	0	75
Nov 2013	52	0	102
Dec 2013	57	0	159
Jan 2014	63	0	105
Feb 2014	51	0	93
Mar 2014	60	1	91
Apr 2014	52	3	120
May 2014	65	1	79
Jun 2014	47	0	50
Jul 2014	72	0	63
Aug 2014	58	1	46
Sep 2014	98	4	64
Oct 2014	151	0	57
Nov 2014	62	0	62
Dec 2014	103	0	46
Jan 2015	103	0	26
Feb 2015	59	1	50
Mar 2015	54	2	111
Apr 2015	58	0	108
May 2015	40	7	137
Jun 2015	41	0	91
Jul 2015	40	1	51
Aug 2015	45	0	59
Sep 2015	65	2	89
Oct 2015	56	13	154
Nov 2015	44	2	108
Dec 2015	48	0	80
Jan 2016	59	0	104
Feb 2016	38	0	83
Mar 2016	44	3	110
Apr 2016	53	0	131
May 2016	116	0	99
Jun 2016	48	0	59
Jul 2016	64	0	61
Aug 2016	74	0	63
Sep 2016	86	0	80
Oct 2016	79	0	62
Nov 2016	80	0	90
Dec 2016	42	0	53
Jan 2017	76	0	68
Feb 2017	70	0	46
Mar 2017	87	0	88
Apr 2017	55	0	64
May 2017	46	0	38
Jun 2017	45	0	60
Jul 2017	35	0	105
Aug 2017	43	0	91
Sep 2017	62	0	94
Oct 2017	42	0	122
Nov 2017	41	0	89
Dec 2017	33	0	77
Jan 2018	67	0	93
Feb 2018	78	0	43
Mar 2018	68	0	66
Apr 2018	94	0	43
May 2018	73	0	35
Jun 2018	76	0	40
Jul 2018	57	0	101
Aug 2018	45	0	59
Sep 2018	60	0	109
Oct 2018	84	0	73
Nov 2018	79	0	73
Dec 2018	76	0	31
Jan 2019	75	0	63
Feb 2019	95	0	71
Mar 2019	69	0	57
Apr 2019	43	0	71
May 2019	72	0	73
Jun 2019	54	0	79
Jul 2019	69	0	36
Aug 2019	41	0	27
Sep 2019	60	0	41
Oct 2019	84	0	37
Nov 2019	44	0	35
Dec 2019	52	0	38
Jan 2020	31	0	20
Feb 2020	50	0	17
Mar 2020	51	0	31
Apr 2020	43	0	23
May 2020	39	0	39
Jun 2020	35	0	33
Jul 2020	31	0	18
Aug 2020	53	0	47
Sep 2020	66	0	31
Oct 2020	74	0	31
Nov 2020	102	0	37
Dec 2020	137	0	36
Jan 2021	37	0	14

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Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo.

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Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo.

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