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Clinical Care/Education/Nutrition

High-Intensity Resistance Training Improves Glycemic Control in Older Patients With Type 2 Diabetes

  1. David W. Dunstan, PHD1,
  2. Robin M. Daly, PHD2,
  3. Neville Owen, PHD3,
  4. Damien Jolley, MSC2,
  5. Maximilian de Courten, MD1,
  6. Jonathan Shaw, MD1 and
  7. Paul Zimmet, PHD1
  1. 1International Diabetes Institute, Melbourne, Australia
  2. 2School of Health Sciences, Deakin University, Melbourne, Australia
  3. 3School of Population Health, University of Queensland, Brisbane, Australia
    Diabetes Care 2002 Oct; 25(10): 1729-1736. https://doi.org/10.2337/diacare.25.10.1729
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    Abstract

    OBJECTIVE—To examine the effect of high-intensity progressive resistance training combined with moderate weight loss on glycemic control and body composition in older patients with type 2 diabetes.

    RESEARCH DESIGN AND METHODS—Sedentary, overweight men and women with type 2 diabetes, aged 60–80 years (n = 36), were randomized to high-intensity progressive resistance training plus moderate weight loss (RT & WL group) or moderate weight loss plus a control program (WL group). Clinical and laboratory measurements were assessed at 0, 3, and 6 months.

    RESULTS—HbA1c fell significantly more in RT & WL than WL at 3 months (0.6 ± 0.7 vs. 0.07 ± 0.8%, P < 0.05) and 6 months (1.2 ± 1.0 vs. 0.4 ± 0.8%, P < 0.05). Similar reductions in body weight (RT & WL 2.5 ± 2.9 vs. WL 3.1 ± 2.1 kg) and fat mass (RT & WL 2.4 ± 2.7 vs. WL 2.7 ± 2.5 kg) were observed after 6 months. In contrast, lean body mass (LBM) increased in the RT & WL group (0.5 ± 1.1 kg) and decreased in the WL group (0.4 ± 1.0) after 6 months (P < 0.05). There were no between-group differences for fasting glucose, insulin, serum lipids and lipoproteins, or resting blood pressure.

    CONCLUSIONS—High-intensity progressive resistance training, in combination with moderate weight loss, was effective in improving glycemic control in older patients with type 2 diabetes. Additional benefits of improved muscular strength and LBM identify high-intensity resistance training as a feasible and effective component in the management program for older patients with type 2 diabetes.

    • 1-RM, one-repetition maximum strength
    • HOMA, homeostasis model assessment
    • LBM, lean body mass
    • RT & WL group, high-intensity progressive resistance training plus moderate weight loss group
    • WL group, moderate weight loss plus a control program group

    Footnotes

    • Address correspondence and reprint requests to Dr. David Dunstan, International Diabetes Institute, 250 Kooyong Rd., Caulfield, Victoria, Australia 3162. E-mail: ddunstan{at}idi.org.au.

      Received for publication 26 May 2002 and accepted in revised from 12 July 2002.

      A table elsewhere in this issue shows conventional and Système International (SI) units and conversion factors for many substances.

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    High-Intensity Resistance Training Improves Glycemic Control in Older Patients With Type 2 Diabetes
    David W. Dunstan, Robin M. Daly, Neville Owen, Damien Jolley, Maximilian de Courten, Jonathan Shaw, Paul Zimmet
    Diabetes Care Oct 2002, 25 (10) 1729-1736; DOI: 10.2337/diacare.25.10.1729

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    High-Intensity Resistance Training Improves Glycemic Control in Older Patients With Type 2 Diabetes
    David W. Dunstan, Robin M. Daly, Neville Owen, Damien Jolley, Maximilian de Courten, Jonathan Shaw, Paul Zimmet
    Diabetes Care Oct 2002, 25 (10) 1729-1736; DOI: 10.2337/diacare.25.10.1729
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