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OtherClinical Care/Education/Nutrition

Effect of Leptin Replacement on Intrahepatic and Intramyocellular Lipid Content in Patients With Generalized Lipodystrophy

Vinaya Simha, Lidia S. Szczepaniak, Anthony J. Wagner, Alex M. DePaoli, Abhimanyu Garg
DOI: 10.2337/diacare.26.1.30 Published 1 January 2003
Vinaya Simha
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Lidia S. Szczepaniak
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Anthony J. Wagner
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Alex M. DePaoli
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Abhimanyu Garg
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Figure 1—

Changes in intrahepatic (A) and intramyocellular (B) lipid content in three patients with generalized lipodystrophy treated with human recombinant leptin for 8–10 months. The corresponding changes in insulin sensitivity, measured as the rate of glucose disappearance during the insulin tolerance test (K value) are shown in C.

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Diabetes Care: 44 (4)

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April 2021, 44(4)
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