Meta-Analysis of Low-Glycemic Index Diets in the Management of Diabetes: Response to Brand-Miller et al. and Mann

Letters: Comments and Responses

Meta-Analysis of Low-Glycemic Index Diets in the Management of Diabetes

Address correspondence to Marion J. Franz, MS, RD, CDE, Nutrition Concepts by Franz, Inc., 6635 Limerick Dr., Minneapolis, MN 55439. E-mail: marionfranz{at}aol.com

Table 1

Changes in HbA_1c from baseline to study end from low- and high-glycemic index diets

Reference, number of subjects (n), and study length	Baseline HbA_1c: low- vs. high-GI diet	Study end HbA_1c: low- vs. high-GI diet	HbA_1c changes from baseline with the implementation of the low-GI diet
Heilbronn et al. (4), n = 45, 4 wks on weight loss diet followed by 8 weeks on weight loss diets of low or high GI	6.7%, after 4 wks of weight loss diets: 6.65 vs. 6.35%	6.04 vs. 6.06%	After implementation of the GI diets, a 0.6% decrease in low GI, not significantly different than high-GI diet; no difference in weight loss from low- vs. high-GI diets
Gilbertson et al. (10), n = 104, 52 weeks	8.3 vs. 8.6%	8.0 vs. 8.6%	0.3% decrease in low-GI group, although reported GIs were the same in both groups at study end
Giacco et al. (11), n = 63, 24 weeks	8.8 vs. 8.8%	8.6% (compliant group) vs. 9.1%	0.2% decrease in low-GI compliant group
Brand et al. (12), n = 16, 12 weeks	7.7 vs. 7.7%	7.0 vs. 7.9%	0.7% decrease in low-GI group
Collier, et al. (12), n = 7, 6 weeks	10.0 vs. 9.9%	10.0 vs. 9.86%	No difference at study end