Screening for Celiac Disease in Children With Type 1 Diabetes: Two views of the controversy

Point-Counterpoint

Screening for Celiac Disease in Children With Type 1 Diabetes

¹Department of Pediatrics, Duke University Medical Center, Durham, North Carolina
²Pediatric Endocrine Unit, Mass General Hospital for Children, Harvard Medical School, Boston, Massachusetts

Diabetes Care 2003 Jun; 26(6): 1932-1939. https://doi.org/10.2337/diacare.26.6.1932

Table 1—

Summary of published studies of children with type 1 diabetes screened for celiac disease with endomysial or tissue transglutaminase antibodies

Source	Positive screen	Positive biopsy	Symptoms	Diet improved
Denmark (56)	10/104 (9.6%)	9/9	6/9	5/6 (4 refused)
British Columbia (57)	18/232 (7.7%)	14/18	10/18	NI
Wisconsin (58)	17/218 (7.8%)	10/14	3/10	2/3
Germany (59)	13/205 (6.3%)	7/8	3/8	NI
Italy (49)	27/273 (9.9%)	16/20	2/16	2/2
New York (60)	10/211 (4.7%)	3/3	NI	NI
North Carolina/ Maryland (61)	3/81 (3.7%)	1/3	0/3	NI
Total	98/1324 (7.4%)	60/75 (80%)	24/64 (37.5%)	9/11 (81.8%)