Right Ventricular Dysfunction in Asymptomatic Diabetic Patients
Article Figures & Tables
Figures
- Figure 1—
Examples of right ventricular myocardial velocity curves in a healthy subject (A) and diabetic patient (B). Both Em and Em-to-Am ratio are lower (9.0 vs. 11.1 cm/s and 0.88 vs. 1.09, respectively) and IRTm longer (60 vs. 37 ms) in the patient with diabetes.
Tables
- Table 1—
Clinical and echocardiographic data in diabetic patients and control subjects
DMN group DMHT group Control group DMN vs. control DMHT vs. control DMN vs. DMHT n 27 36 33 — — — Age (years) 58.5 ± 11.3 56.6 ± 9.9 58.2 ± 7.9 NS NS NS Male sex 14 (52) 21 (58) 17 (51) NS NS NS Duration of diabetes (years) 10.1 ± 7.3 9.3 ± 5.9 — — — NS Type of diabetes (type 1/type 2) 3/24 4/32 — — — NS Systolic blood pressure (mmHg) 128.2 ± 12.3 163.5 ± 16.2 125.7 ± 11.1 NS 0.001 0.001 Diastolic blood pressure (mmHg) 76.5 ± 5.9 95.0 ± 8.3 74.3 ± 7.1 NS 0.001 0.001 BMI (kg/m2) 26.6 ± 4.6 28.3 ± 3.3 26.5 ± 3.9 NS NS NS Fasting plasma glucose (mmol/l) 8.0 ± 2.4 8.3 ± 2.2 4.7 ± 0.47 0.001 0.001 NS HbA1c(%) 7.5 ± 1.9 7.7 ± 1.8 — — — NS Diabetic retinopathy 9 (33) 13 (36) — — — NS Microalbuminuria/proteinuria 6 (22) 9 (25) — — — NS Insulin 11 (41) 16 (44) 0 (0) — — NS Sulfonylureas 14 (52) 20 (56) 0 (0) — — NS Metformin 6 (22) 10 (28) 0 (0) — — NS Left ventricular ejection fraction (%) 66.2 ± 6.4 67.1 ± 7.6 66.2 ± 9.2 NS NS NS Right ventricular end-diastolic dimension (mm) 20.8 ± 2.9 21.3 ± 2.7 20.9 ± 3.0 NS NS NS Right ventricular free wall thickness (mm) 3.8 ± 0.8 4.0 ± 1.0 3.7 ± 0.7 NS NS NS TPSE (mm) 19.7 ± 3.1 20.1 ± 3.2 19.8 ± 2.7 NS NS NS Right ventricular E-to-A ratio 1.17 ± 0.25 1.14 ± 0.17 1.19 ± 0.18 NS NS NS Right ventricular IRT (ms) 54.3 ± 17.3 54.1 ± 19.2 43.2 ± 15.5 0.03 0.02 NS Right ventricular basal segment Sm (cm/s) 11.8 ± 0.91 12.3 ± 2.34 12.2 ± 1.63 NS NS NS Right ventricular basal segment Em (cm/s) 9.1 ± 1.91 8.8 ± 1.84 10.5 ± 1.95 0.007 0.003 NS Right ventricular basal segment Em-to-Amratio 0.80 ± 0.20 0.79 ± 0.17 0.91 ± 0.22 0.05 0.02 NS Right ventricular basal segment IRTm (ms) 40.6 ± 12.8 41.7 ± 14.6 37.7 ± 12.9 NS NS NS Right ventricular mid-segment Sm (cm/s) 9.5 ± 1.5 9.6 ± 2.0 9.7 ± 1.73 NS NS NS Right ventricular mid-segment Em (cm/s) 7.8 ± 1.49 7.7 ± 1.60 8.9 ± 1.84 0.01 0.007 NS Right ventricular mid-segment Em-to-Am ratio 0.87 ± 0.20 0.88 ± 0.18 0.97 ± 0.19 0.04 0.04 NS Right ventricular mid-segment IRTm (ms) 50.8 ± 14.4 50.2 ± 12.3 42.3 ± 9.6 0.009 0.006 NS -
Data are n (%) or means ± SD. E-to-A ratio, peak early–to–peak late diastolic velocity ratio; TPSE, tricuspid plane systolic excursion.
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In this Issue
November 2004, 27(11)
Right Ventricular Dysfunction in Asymptomatic Diabetic Patients
