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Emerging Treatments and Technologies

Continuous Glucose Monitoring and the Reality of Metabolic Control in Preschool Children With Type 1 Diabetes

  1. George S. Jeha, MD12,
  2. Lefkothea P. Karaviti, MD, PHD12,
  3. Barbara Anderson, PHD1,
  4. E. O’Brian Smith, PHD1,
  5. Susan Donaldson, RN2,
  6. Toniean S. McGirk, RN2 and
  7. Morey W. Haymond, MD12
  1. 1Section of Pediatric Endocrinology and Metabolism, Baylor College of Medicine, Houston, Texas
  2. 2Section of Pediatric Endocrinology and Metabolism, Texas Children’s Hospital, Houston, Texas
  1. Address correspondence and reprint requests to George Jeha, MD, Texas Children’s Hospital, Clinical Care Center, Suite 1020, 6621 Fannin St., CC 1020.05, Houston, TX 77030. E-mail: gsjeha{at}texaschildrenshospital.org
Diabetes Care 2004 Dec; 27(12): 2881-2886. https://doi.org/10.2337/diacare.27.12.2881
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    Figure 1—

    A: Accuracy analysis. The 379 pairs of glucose values were plotted against each other with the meter on the x-axis and CGMS on the y-axis. The graph was divided into four areas by a line crossing the value of 60 mg/dl on each axis. The areas were labeled as true positive (TP), true negative (TN), false-positive (FP), and false negative (FN), respectively, depending on where the point fell on the graph. The number of true positive was 26, true negative 339, false-positive 3, and false negative 11. B: Clarke error grid analysis. A total of 379 paired values were plotted using the Clarke error grid. Of the values, 97.4% fell within the clinically acceptable A and B regions (n = 369), 81.3% fell in zone A, and 16.1% in zone B. Only one measurement fell in the upper C region (0.3%) and nine in the upper D region (2.3%).

  • Figure 2—
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    Figure 2—

    Pie chart depicting the glycemic trends obtained from the CGMS during a 24-h period. Each portion corresponds to a glucose range. The legend below the figure depicts the different ranges. The proportion of the time spent within any given range is expressed as a percentage and shown next to each portion.

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  • Table 1—

    The 24-h distribution of hpyoglycemic episodes

    Hypoglycemic episodesMedian per subjectRange
    Total duration of monitoring (h)70.049–90.5
    Total number of episodes per 24 h (h)1.10–4
    Number of nighttime episodes per 24 h0.80–2
    Number of daytime episodes per 24 h0.30–2
    Total duration of episodes per 24 h (h)1.40–5.3
    Duration of night time episodes (h)1.20–5.3
    Duration of daytime episodes (h)0.20–1.3
    • Summary of the number, duration, and night/day distribution of hypoglycemic episodes recorded by the CGMS.

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Diabetes Care: 27 (12)

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December 2004, 27(12)
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Continuous Glucose Monitoring and the Reality of Metabolic Control in Preschool Children With Type 1 Diabetes
George S. Jeha, Lefkothea P. Karaviti, Barbara Anderson, E. O’Brian Smith, Susan Donaldson, Toniean S. McGirk, Morey W. Haymond
Diabetes Care Dec 2004, 27 (12) 2881-2886; DOI: 10.2337/diacare.27.12.2881

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Continuous Glucose Monitoring and the Reality of Metabolic Control in Preschool Children With Type 1 Diabetes
George S. Jeha, Lefkothea P. Karaviti, Barbara Anderson, E. O’Brian Smith, Susan Donaldson, Toniean S. McGirk, Morey W. Haymond
Diabetes Care Dec 2004, 27 (12) 2881-2886; DOI: 10.2337/diacare.27.12.2881
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