The Prospective Pioglitazone Clinical Trial in Macrovascular Events (PROactive): Can pioglitazone reduce cardiovascular events in diabetes? Study design and baseline characteristics of 5,238 patients

Bernard Charbonnel; John Dormandy; Erland Erdmann; Massimo Massi-Benedetti; Allan Skene

doi:10.2337/diacare.27.7.1647

Epidemiology/Health Services/Psychosocial Research

The Prospective Pioglitazone Clinical Trial in Macrovascular Events (PROactive)

Can pioglitazone reduce cardiovascular events in diabetes? Study design and baseline characteristics of 5,238 patients

Bernard Charbonnel, MD1,
John Dormandy, FRCS(ED), FRCS(ENG), DSC2,
Erland Erdmann, MD, FESC, FACC3,
Massimo Massi-Benedetti, MD4,
Allan Skene, PHD5 and
PROactive Study Group

¹Clinique d’Endocrinologie, Nantes Cedex, France
²Department of Vascular Surgery, St. George’s Hospital, London, U.K
³Klinik III für Innere Medizin, Köln, Germany
⁴Dipartimento di Medicina Interna, Università di Perugia, Perugia, Italy
⁵Nottingham Clinical Research Limited, Isaac Newton Centre, Nottingham Science and Technology Park, Nottingham, U.K

Address correspondence and reprint requests to Professor Bernard Charbonnel, MD, PROactive, Clinique d’Endocrinologie, Hotel Dieu, Place Alexis Ricordeau, 44093 Nantes Cedex 1, France. E-mail: bernard.charbonnel{at}sante.univ-nantes.fr

Diabetes Care 2004 Jul; 27(7): 1647-1653. https://doi.org/10.2337/diacare.27.7.1647

Article Information

vol. 27 no. 7 1647-1653

DOI

https://doi.org/10.2337/diacare.27.7.1647

PubMed

15220241

Published By

American Diabetes Association

Print ISSN

0149-5992

Online ISSN

1935-5548

History

April 5, 2004
October 5, 2003
Published in print June 25, 2004.

DIABETES CARE

Author Information

Bernard Charbonnel, MD1,
John Dormandy, FRCS(ED), FRCS(ENG), DSC2,
Erland Erdmann, MD, FESC, FACC3,
Massimo Massi-Benedetti, MD4,
Allan Skene, PHD5 and
PROactive Study Group

¹Clinique d’Endocrinologie, Nantes Cedex, France
²Department of Vascular Surgery, St. George’s Hospital, London, U.K
³Klinik III für Innere Medizin, Köln, Germany
⁴Dipartimento di Medicina Interna, Università di Perugia, Perugia, Italy
⁵Nottingham Clinical Research Limited, Isaac Newton Centre, Nottingham Science and Technology Park, Nottingham, U.K

Address correspondence and reprint requests to Professor Bernard Charbonnel, MD, PROactive, Clinique d’Endocrinologie, Hotel Dieu, Place Alexis Ricordeau, 44093 Nantes Cedex 1, France. E-mail: bernard.charbonnel{at}sante.univ-nantes.fr

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