Use of Insulin Glargine During the First Weeks of Pregnancy in Five Type 1 Diabetic Women
- Graziano Di Cianni, MD,
- Laura Volpe, MD,
- Cristina Lencioni, MD,
- Kyriazoula Chatzianagnostou, MD,
- Ilaria Cuccuru, MD,
- Alessandra Ghio, MD,
- Luca Benzi, MD and
- Stefano Del Prato, MD
- From the Department of Endocrinology and Metabolism, Section of Diabetes, University of Pisa, Pisa, Italy
- Address correspondence to Dr. Graziano Di Cianni, Department of Endocrinology and Metabolism, Section of Diabetes and Metabolic Diseases, Ospedale di Cisanello, Via Paradisa, 2, I-56126 Pisa, Italy. E-mail: dicianni{at}immr.med.unipi.it
Article Figures & Tables
Tables
- Table 1—
Clinical characteristics of five type 1 diabetic pregnancies
Patient Age (years)/ white class* HbA1c preconception/ end of pregnancy (%) Use of glargine in pregnancy (weeks) Glargine dose in pregnancy (IU/day) Time of delivery (weeks) Newborn weight (g) Perinatal mortality and/or congenital malformation 1 32/B 7.0/6.7 6 18 35 2,220 No 2 26/C 6.4/6.4 12 56 37 3,500 No 3 41/C 7.0/6.2 8 18 38 4,400 No 4 32/D 7.6/5.8 6 14 37 2,850 No 5 27/B 8.7/5.8 6 20 36 2,360 No - *
↵* White Classification of Diabetes in Pregnancy (7). Class A: Diet alone, any duration or onset age. Class B: Onset at age ≥20 years, duration <10 years. Class C: Onset between the ages of 10 and 19 years, duration 10–19 years. Class D: Onset before the age of 10 years, duration <20 years, background retinopathy or hypertension (not pre-eclampsia). Class R: Proliferative retinopathy or vitreous hemorrhage. Class F: Nephropathy with >500 mg/day proteinuria. Class RF: Criteria for both classes R and F coexist. Class H: Arteriosclerotic hearth disease clinically evident. Class T: Prior renal transplantation. All classes below A require insulin therapy.
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In this Issue
April 2005, 28(4)
Use of Insulin Glargine During the First Weeks of Pregnancy in Five Type 1 Diabetic Women
