Is Pregnancy Outcome Worse in Type 2 Than in Type 1 Diabetic Women?
- Natalia Hillman, MD,
- Lucrecia Herranz, MD, PHD,
- Pilar M. Vaquero, MD,
- Africa Villarroel, MD,
- Alberto Fernandez, BM and
- Luis F. Pallardo, MD, PHD
- From the Division of Diabetes, Department of Endocrinology and Nutrition, University Hospital La Paz, Madrid, Spain
- Address correspondence to Natalia Hillman Gadea, Division of Diabetes, Department of Endocrinology and Nutrition, University Hospital La Paz, 28046 Madrid, Spain. E-mail: nhillman.hulp{at}salud.madrid.org
Article Figures & Tables
Tables
- Table 1—
Maternal and perinatal outcomes
Type 2 diabetes Type 1 diabetes P n* 93 532 Prepregnancy BMI (kg/m2) 28.9 ± 6.5 23.3 ± 3.1 <0.001 Maternal weight gain during pregnancy (kg) 11.7 ± 5.0 13.7 ± 4.2 <0.001 Glycemic control during pregnancy A1C at admission (%) 6.4 ± 1.19 7.2 ± 1.19 <0.001† A1C second trimester (%) 5.8 ± 0.84 6.3 ± 0.9 <0.001† A1C third trimester (%) 5.8 ± 0.76 6.2 ± 0.8 0.001† Insulin requirements First trimester (units/kg) 0.38 ± 0.19 0.68 ± 0.18 <0.001† Second trimester (units/kg) 0.48 ± 0.23 0.76 ± 0.21 <0.001† Third trimester (units/kg) 0.62 ± 0.31 0.93 ± 0.26 <0.001† Pregnancy-induced hypertension 18 (19.4) 82 (15.4) 0.358 Preeclampsia 6 (6.5) 17 (3.2) 0.134 Caesarean delivery 41 (44.1) 298 (56) 0.032 Gestational age (weeks of gestation) 37.1 ± 1.6 36.7 ± 1.7 0.018 Preterm delivery 28 (30.4) 186 (35.4) 0.406 Birth weight (g) 3,182 ± 623 3,243 ± 606 0.375 Birth weight ratio 1.09 ± 0.2 1.13 ± 0.18 0.019 Large for gestational age 22 (23.9) 187 (35.6) 0.032 Small for gestational age 3 (3.3) 5 (1) 0.100 Perinatal mortality 1 (1.1) 9 (1.7) 1.000 Major congenital malformations 6 (6.5) 25 (4.7) 0.442 Neonatal hypoglycemia 24 (26.1) 172 (32.8) 0.226 Neonatal hyperbilirrubinemia 34 (37) 223 (42.5) 0.359 Neonatal hypocalcemia 4 (4.3) 30 (5.7) 0.805 Birth trauma 7 (7.6) 29 (5.5) 0.467 Neonatal sepsis 9 (9.8) 55 (10.5) 1.000 Neonatal polycythemia 14 (15.2) 71 (13.5) 0.626 Neonatal respiratory distress syndrome 7 (7.6) 95 (18.1) 0.010
In this Issue
November 2006, 29(11)
Is Pregnancy Outcome Worse in Type 2 Than in Type 1 Diabetic Women?
