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Epidemiology/Health Services Research

Cost-Effectiveness of the Interventions in the Primary Prevention of Diabetes Among Asian Indians

Within-trial results of the Indian Diabetes Prevention Programme (IDPP)

  1. Ambady Ramachandran, DSC1,
  2. Chamukuttan Snehalatha, DSC1,
  3. Annasami Yamuna, PHD1,
  4. Simon Mary, BSC1 and
  5. Zhang Ping, PHD2
  1. 1India Diabetes Research Foundation, and Dr. A. Ramachandran’s Diabetes Hospitals, Chennai, India
  2. 2Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia
  1. Address correspondence and reprint requests to Prof. A. Ramachandran, India Diabetes Research Foundation and Dr. A. Ramachandran’s Diabetes Hospitals, 28, Marshall’s Road, Egmore, Chennai 600008, India. E-mail: ramachandran{at}vsnl.com
Diabetes Care 2007 Oct; 30(10): 2548-2552. https://doi.org/10.2337/dc07-0150
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Article Figures & Tables

Tables

  • Table 1—

    Components of expenditure considered for direct medical costs incurred during the intervention period of 3 years in various arms of the study

    Item and providerUnits (n/3 years)
    Time (h spent/3 years)
    Total cost in INR
    ControlLSMMetLSM + MetControlLSMMetLSM + MetControlLSMMetLSM + Met
    Standard lifestyle cost2,739
    Expenditure—laboratories
        Drug cost1,5611,561
    Visits375375
        Physician0121012—1.50.991.51,2926201,292
        Social worker4127120.832.250.662.254750493504
        Dietician1121120.162.250.332.251053120531
        Helper1125120.161.50.581.5933665336
        Technician0686—0.480.480.48607560
    Phone calls
        Social worker13910390.051.980.241.98374533745
        Dietician039039—1.98—1.98777—777
        Helper204800.10—0.41—6—263—
        Secretary33636720.150.150.250.1567878156
    Overhead charges813900846894
    Travel cost1,8454,9133,1134,913
    Total INR (U.S. $)2,739 (61)10,136 (225)9,881 (220)12,144 (270)
    • Met, metformin.

  • Table 2—

    Summary of the total and incremental costs of the interventions of IDPP and sensitivity analysis with hypothetical models

    Type of interventionCost of intervention
    ControlLSMMetLSM + Met
    1st year939 (21)3883 (86)3,568 (79)4,571 (102)
    2nd year900 (20)2594 (58)3,069 (68)3,254 (72)
    3rd year900 (20)3659 (81)3,244 (72)4,319 (96)
    Total2,739 (61)10,136 (225)9,881 (220)12,144 (270)
    No. needed to prevent one case of diabetes (NNT)—6.46.96.5
    Incremental cost (IC)—7,397 (164)7,142 (159)9,405 (209)
    CER: IC × NNT—47,341 (1,052)49,280 (1,095)61,133 (1,359)
    Sensitivity analysis (CER)
        No physician, effectiveness 10% less42,979 (955)49,176 (1,093)57,927 (1,287)
        Group sessions, effectiveness same37,670 (837)47,886 (1,064)51,311 (1,140)
        Group sessions, effectiveness 10% more33,903 (753)43,444 (965)46,259 (1,028)
    • Data are INR (U.S. $). CER, cost-effectiveness ratio; Met, metformin.

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Diabetes Care: 30 (10)

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October 2007, 30(10)
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Cost-Effectiveness of the Interventions in the Primary Prevention of Diabetes Among Asian Indians
Ambady Ramachandran, Chamukuttan Snehalatha, Annasami Yamuna, Simon Mary, Zhang Ping
Diabetes Care Oct 2007, 30 (10) 2548-2552; DOI: 10.2337/dc07-0150

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Cost-Effectiveness of the Interventions in the Primary Prevention of Diabetes Among Asian Indians
Ambady Ramachandran, Chamukuttan Snehalatha, Annasami Yamuna, Simon Mary, Zhang Ping
Diabetes Care Oct 2007, 30 (10) 2548-2552; DOI: 10.2337/dc07-0150
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