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Clinical Care/Education/Nutrition

Prediction of Severe Hypoglycemia

  1. Daniel J. Cox, PHD1,
  2. Linda Gonder-Frederick, PHD1,
  3. Lee Ritterband, PHD1,
  4. William Clarke, MD2 and
  5. Boris P. Kovatchev, PHD1
  1. 1Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Health System, Charlottesville, Virginia
  2. 2Department of Pediatrics, University of Virginia Health System, Charlottesville, Virginia
  1. Address correspondence and reprint requests to Daniel J. Cox, PhD, University of Virginia Health System, Box 800137, Charlottesville, VA 22908. E-mail: djc4f{at}virginia.edu
Diabetes Care 2007 Jun; 30(6): 1370-1373. https://doi.org/10.2337/dc06-1386
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    Figure 1—

    The ratio of LBGI to its baseline in the 3 days preceding and 2 days following an episode of SH for individuals with type 1 (T1DM) and type 2 (T2DM) diabetes.

Tables

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  • Table 1—

    Demographic characteristics and SMBG frequency of the participants

    Type 1 diabetesType 2 diabetes
    n9070
    Average age (years)40.7 ± 11.250.2 ± 8.0
    Sex (% male)4339
    Caucasian/African American/Hispanic/Native American (%)96/3/1/071/27/0/2
    BMI (kg/m2)25.3 ± 4.436.3 ± 9.2
    Duration of diabetes (years)20.0 ± 10.712.2 ± 8.5
    Insulin (units · kg−1 · day−1)0.48 ± 0.260.56 ± 0.25
    A1C (%)7.6 ± 1.28.8 ± 2.0
    Number of SH episodes in the last year (average per person)1.30.3
    Percent of subjects who experienced at least one SH in the past year (%)3610
    SMBG readings per day during the study5.4 ± 2.33.5 ± 0.8
    • Data are means ± SD, unless otherwise indicated.

  • Table 2—

    Prediction of upcoming (within 24 h) SH and mild hypoglycemia

    Minimum number of SMBG readings in the 24 h preceding the episodePercent predicted SH episodes
    Accuracy in type 1 diabetes358
    460
    560
    Accuracy in type 2 diabetes360
    464
    573
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Diabetes Care: 30 (6)

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June 2007, 30(6)
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Prediction of Severe Hypoglycemia
Daniel J. Cox, Linda Gonder-Frederick, Lee Ritterband, William Clarke, Boris P. Kovatchev
Diabetes Care Jun 2007, 30 (6) 1370-1373; DOI: 10.2337/dc06-1386

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Prediction of Severe Hypoglycemia
Daniel J. Cox, Linda Gonder-Frederick, Lee Ritterband, William Clarke, Boris P. Kovatchev
Diabetes Care Jun 2007, 30 (6) 1370-1373; DOI: 10.2337/dc06-1386
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