TRIB3 Functional Q84R Polymorphism Is a Risk Factor for Metabolic Syndrome and Carotid Atherosclerosis
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Tables
- Table 1
Clinical and biochemical characteristics of subjects by TRIB3 Q84R genotype in MetS group
QQ84 (n = 125) QR84 (n = 79) RR84 (n = 13) P P* vs. QQ84 group vs. QR84 group vs. QQ84 group vs. QR84 group Sex (male/female) 51/74 39/40 9/4 0.076 0.237 Age (years) 55.15 ± 9.14 54.71 ± 9.84 56.85 ± 6.40 0.532 0.442 BMI (kg/m2) 28.95 ± 4.31 28.80 ± 3.90 29.61 ± 2.80 0.581 0.508 Systolic blood pressure (mmHg) 152.19 ± 22.11 148.10 ± 20.72 156.85 ± 28.47 0.471 0.187 Diastolic blood pressure (mmHg) 94.14 ± 14.00 93.35 ± 13.74 91.62 ± 16.05 0.539 0.681 Waist circumference (cm) 98.01 ± 9.73 97.37 ± 10.42 101.31 ± 8.81 0.259 0.188 Waist-to-hip ratio 0.93 ± 0.06 0.93 ± 0.06 0.96 ± 0.04 0.041 0.041 Total cholesterol (mmol/l) 5.29 ± 1.29 5.48 ± 1.10 6.03 ± 0.87 0.038 0.130 0.056 0.198 Triglycerides (mmol/l) 2.04 ± 0.92 2.57 ± 1.64 2.77 ± 1.24 0.047 0.587 0.008 0.847 HDL cholesterol (mmol/l) 1.25 ± 0.30 1.24 ± 0.42 1.04 ± 0.19 0.034 0.047 0.077 0.063 LDL cholesterol (mmol/l) 3.49 ± 0.94 3.58 ± 0.96 4.06 ± 1.07 0.044 0.098 0.033 0.088 Fasting blood glucose (mmol/l) 6.69 ± 2.41 6.64 ± 2.71 6.13 ± 2.47 0.446 0.501 Insulin (μU/ml) 20.47 ± 10.76 20.04 ± 9.67 19.23 ± 14.68 0.694 0.802 HOMA-IR 6.30 ± 4.71 5.84 ± 3.22 5.24 ± 4.50 0.389 0.639 Normal IMT 80 41 2 0.001 0.017 Mean IMT (mm) 0.75 ± 0.15 0.76 ± 0.18 0.95 ± 0.18 0.00007 0.0002 Maximum IMT (mm) 1.07 ± 0.69 1.23 ± 0.88 2.44 ± 1.17 0.00000005 0.000002 -
Data are means ± SD unless otherwise indicated.
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↵*P, adjusted for waist-to-hip ratio, sex, age, and smoking. HOMA-IR, homeostasis model assessment for insulin resistance.
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In this Issue
July 2009, 32(7)
TRIB3 Functional Q84R Polymorphism Is a Risk Factor for Metabolic Syndrome and Carotid Atherosclerosis
