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Original Research

Effects of the Dietary Approaches to Stop Hypertension (DASH) Eating Plan on Cardiovascular Risks Among Type 2 Diabetic Patients

A randomized crossover clinical trial

  1. Leila Azadbakht, PHD1,2,
  2. Nafiseh Rashidi Pour Fard, BSC3,
  3. Majid Karimi, MD3,
  4. Mohammad Hassan Baghaei, PHD3,
  5. Pamela J. Surkan, PHD4,
  6. Majid Rahimi, MSC3,
  7. Ahmad Esmaillzadeh, PHD1,2 and
  8. Walter C. Willett, MD, DRPH5,6
  1. 1Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran;
  2. 2Department of Nutrition, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran;
  3. 3Shaheed Motahari Hospital, Fooladshahr, Isfahan, Iran;
  4. 4Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland;
  5. 5Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts;
  6. 6Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts.
  1. Corresponding author: Leila Azadbakht, azadbakht{at}hlth.mui.ac.ir.
Diabetes Care 2011 Jan; 34(1): 55-57. https://doi.org/10.2337/dc10-0676
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Article Figures & Tables

Tables

  • Table 1

    Means of the cardiometabolic variables among type 2 diabetic patients after consumption of the DASH or control diet

    Control diet*DASH diet†P‡
    n3131
    Weight (kg)
        Baseline75.0 ± 1.773.4 ± 1.80.001
        End of trial72.9 ± 1.868.4 ± 1.70.001
        Change−2.0 ± 0.3−5.0 ± 0.90.006
    Waist circumference (cm)
        Baseline104.6 ± 1.9103.4 ± 2.00.01
        End of trial102.7 ± 2.096.6 ± 1.90.001
        Change−1.9 ± 0.4−6.7 ± 1.20.002
    SBP (mmHg)
        Baseline137.4 ± 2.8134.5 ± 3.80.39
        End of trial134.2 ± 3.1120.8 ± 3.20.001
        Change−3.1 ± 2.7−13.6 ± 3.50.02
    DBP (mmHg)
        Baseline81.9 ± 2.281.8 ± 1.70.95
        End of trial81.2 ± 2.972.2 ± 2.70.01
        Change−0.7 ± 3.3−9.5 ± 2.60.04
    FBG (mg/dl)
        Baseline171.8 ± 10.9160.9 ± 10.10.73
        End of trial159.0 ± 8.3131.5 ± 7.30.003
        Change−12.8 ± 6.7−29.4 ± 6.30.04
    A1C (%)
        Baseline7.9 ± 1.97.7 ± 1.90.19
        End of trial7.4 ± 1.76.1 ± 0.50.05
        Change−0.5 ± 0.02−1.7 ± 0.10.04
    TG (mg/dl)
        Baseline189.7 ± 19.3170.7 ± 12.40.17
        End of trial178.7 ± 18.4185.1 ± 13.80.53
        Change−10.9 ± 6.8−14.4 ± 10.70.79
    HDL-C (mg/dl)
        Baseline41.2 ± 1.041.2 ± 1.00.97
        End of trial42.5 ± 1.045.6 ± 1.10.001
        Change1.3 ± 0.74.3 ± 0.90.001
    LDL-C (mg/dl)
        Baseline114.7 ± 3.5118.7 ± 3.60.23
        End of trial111.9 ± 4.1101.5 ± 3.10.02
        Change−2.7 ± 4.8−17.2 ± 3.50.02
    Total cholesterol (mg/dl)
        Baseline213.3 ± 6.0214.9 ± 5.70.80
        End of trial205.0 ± 6.6192.7 ± 4.60.03
        Change−8.3 ± 6.3−22.1 ± 5.70.11
    • Data are means ± SE.

    • ↵*The control diet was a designed to control diabetes. The general recommendation for macronutrient composition of the diet was 50–60% carbohydrates; 15–20% protein and <30% total fat. The amount of simple sugar was less than 5% of calorie intake.

    • ↵†The DASH diet was rich in fruits, vegetables, whole grains, and low-fat dairy products, and low in saturated fat, total fat, cholesterol, refined grains, and sweets. The amount of sodium intake was 2,400 mg per day.

    • ↵‡P values are for comparisons between the two diet periods (general linear model). DBP, diastolic blood pressure; FBG, fasting blood glucose; HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; SBP, systolic blood pressure; TG, triglyceride.

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Effects of the Dietary Approaches to Stop Hypertension (DASH) Eating Plan on Cardiovascular Risks Among Type 2 Diabetic Patients
Leila Azadbakht, Nafiseh Rashidi Pour Fard, Majid Karimi, Mohammad Hassan Baghaei, Pamela J. Surkan, Majid Rahimi, Ahmad Esmaillzadeh, Walter C. Willett
Diabetes Care Jan 2011, 34 (1) 55-57; DOI: 10.2337/dc10-0676

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Effects of the Dietary Approaches to Stop Hypertension (DASH) Eating Plan on Cardiovascular Risks Among Type 2 Diabetic Patients
Leila Azadbakht, Nafiseh Rashidi Pour Fard, Majid Karimi, Mohammad Hassan Baghaei, Pamela J. Surkan, Majid Rahimi, Ahmad Esmaillzadeh, Walter C. Willett
Diabetes Care Jan 2011, 34 (1) 55-57; DOI: 10.2337/dc10-0676
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