Possible Influence of Ileal Neobladder on Assessment of Urinary C-peptide
- Takahiro Zenda, MD1,
- Masaji Miyamoto, MD1,
- Toshimitsu Misaki, MD2 and
- Shuichi Kaneko, MD3
- 1Department of Internal Medicine, Tsurugi Municipal Hospital, Hakusan, Ishikawa, Japan
- 2Department of Urology, Tsurugi Municipal Hospital, Hakusan, Ishikawa, Japan
- 3Department of Gastroenterology, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan
- Corresponding author: Takahiro Zenda, t-zenda{at}tsurugihp.jp.
Urinary C-peptide (UCP) is one of the most popular indicators of insulin secretion by pancreatic β-cells (1,2). However, there are no previous reports discussing the relationship between UCP and neobladder, a new, reconstructed bladder using the ileum after radical cystectomy (3,4). We report a patient with neobladder in whom, among parameters of endogenous insulin production, only the 24-h UCP level was extremely decreased.
A 61-year-old Japanese man with diabetes and atrial fibrillation was hospitalized because of left-sided hemiplegia and motor aphasia caused by thrombotic cerebral infarction. The patient had undergone bladder reconstruction with 66 cm of the ileum after radical cystectomy as the result of cancer 10 years ago. Only a lineal operation scar …
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