Original Research

Effects of Metformin Versus Glipizide on Cardiovascular Outcomes in Patients With Type 2 Diabetes and Coronary Artery Disease

  1. Jie Hong, MD1,
  2. Yifei Zhang, MD1,
  3. Shenghan Lai, MD2,
  4. Ankang Lv, MD1,
  5. Qing Su, MD3,
  6. Yan Dong, MD3,
  7. Zhiguang Zhou, MD4,
  8. Weili Tang, MD4,
  9. Jiajun Zhao, MD5,
  10. Lianqun Cui, MD5,
  11. Dajin Zou, MD6,
  12. Dawang Wang, MD7,
  13. Hong Li, MD8,
  14. Chao Liu, MD9,
  15. Guoting Wu, MD10,
  16. Jie Shen, MD11,
  17. Dalong Zhu, MD12,
  18. Weiqing Wang, MD1,
  19. Weifeng Shen, MD1,
  20. Guang Ning, MD, PHD1⇑,
  21. on behalf of the SPREAD-DIMCAD Investigators*
  1. 1Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
  2. 2Johns Hopkins University School of Medicine, Baltimore, Maryland
  3. 3Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
  4. 4The Second Xiangya Hospital of Central South University, Changsha, China
  5. 5Shandong Provincial Hospital, Shandong University, Jinan, China
  6. 6Chang Hai Hospital, Second Military Medical University, Shanghai, China
  7. 7The First Affiliated Hospital of Wenzhou Medical College, Zhejiang Province, China
  8. 8Sir Run Run Shao Hospital, Zhejiang Province, China
  9. 9Jiangsu Province Hospital, Jiangsu Province, China
  10. 10Shanghai Ten’s People’s Hospital of Tongji University, Shanghai, China
  11. 11Nanfang Hospital, Guangdong Province, China
  12. 12Nanjin Drum Tower Hospital, Jiangsu Province, China
  1. Corresponding author: Guang Ning, guangning{at}medmail.com.cn.

  1. J.H. and Y.Z. contributed equally to this study.

Diabetes Care 2013 May; 36(5): 1304-1311. https://doi.org/10.2337/dc12-0719

Article Figures & Tables

Figures

  • Figure 1
    Figure 1

    SPREAD-DIMCAD trial profile.

  • Figure 2
    Figure 2

    Changes of major clinical and biochemical characteristics at baseline and during follow-up in different groups. HbA1c (A), fasting plasma glucose (B), BMI (C), triglycerides (D), total cholesterol (E), LDL cholesterol (F), HDL cholesterol (G), and estimated glomerular filtration rate (eGFR) (H). Data displayed as means ± SD. P value refers to comparison between the groups.

Tables

  • Table 1
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Diabetes Care: 44 (3)

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Effects of Metformin Versus Glipizide on Cardiovascular Outcomes in Patients With Type 2 Diabetes and Coronary Artery Disease
Jie Hong, Yifei Zhang, Shenghan Lai, Ankang Lv, Qing Su, Yan Dong, Zhiguang Zhou, Weili Tang, Jiajun Zhao, Lianqun Cui, Dajin Zou, Dawang Wang, Hong Li, Chao Liu, Guoting Wu, Jie Shen, Dalong Zhu, Weiqing Wang, Weifeng Shen, Guang Ning, on behalf of the SPREAD-DIMCAD Investigators
Diabetes Care May 2013, 36 (5) 1304-1311; DOI: 10.2337/dc12-0719
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