Quantitative Estimation of Insulin Sensitivity in Type 1 Diabetic Subjects Wearing a Sensor-Augmented Insulin Pump
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Figures
- Figure 1
Data needed for the estimation of insulin sensitivity. Glucose data are measured by CGM (left-hand panel, black line), with some SMBG data available for sensor recalibration (left-hand panel, gray dots). Insulin data are the basal infusion and boluses administered by insulin pump (right-hand panel, black line and gray triangles, respectively).
- Figure 2
Time course of meal rate of appearance, RaG (left-hand panel), and fraction of meal that appears in plasma, f (right-hand panel).
- Figure 3
Mean values (left-hand panel) and correlation plot (right-hand panel) between SIMM and SISP insulin sensitivity indices for breakfast, lunch, and dinner (white, striped, and black bars, respectively). *P < 10−3 with paired sample t test.
- Figure 4
Sensitivity analysis of SISP with (left-hand panel) and without (right-hand panel) accounting for COB for different time integration intervals: mean values of SISP (top), correlation indices (middle), and absolute relative error (bottom), calculated with respect to SISP, i.e., estimated at t = 360 min.
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