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Considerations in the Management of Gestational Diabetes Mellitus

Issues With the Diagnosis and Classification of Hyperglycemia in Early Pregnancy

  1. H. David McIntyre1⇑,
  2. David A. Sacks2,
  3. Linda A. Barbour3,
  4. Denice S. Feig4,
  5. Patrick M. Catalano5,
  6. Peter Damm6 and
  7. Aidan McElduff7
  1. 1Mater Research, The University of Queensland, Brisbane, Queensland, Australia
  2. 2Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA
  3. 3Divisions of Endocrinology, Metabolism and Diabetes and Maternal Fetal Medicine, University of Colorado, Denver, CO
  4. 4Department of Medicine, University of Toronto, Toronto, Ontario, Canada
  5. 5Department of Reproductive Biology, Case Western Reserve University at MetroHealth Medical Center, Cleveland, OH
  6. 6Center for Pregnant Women With Diabetes, Departments of Obstetrics and Endocrinology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
  7. 7Discipline of Medicine, The University of Sydney, Sydney, New South Wales, Australia
  1. Corresponding author: H. David McIntyre, david.mcintyre{at}mater.org.au.
Diabetes Care 2016 Jan; 39(1): 53-54. https://doi.org/10.2337/dc15-1887
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In 2010, the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) panel published consensus-based recommendations on the diagnosis and classification of hyperglycemia in pregnancy (1). Within that document, the recommendations regarding early pregnancy testing were designed to facilitate early detection and treatment of hyperglycemia (HbA1c ≥6.5% [48 mmol/mol], fasting venous plasma glucose ≥7.0 mmol/L, random plasma glucose ≥11.1 mmol/L with confirmation) that, outside pregnancy, would be classified as diabetes. The term “overt diabetes” was suggested to describe these women. Subsequently, the World Health Organization (WHO) adopted the IADPSG criteria with some modifications and promoted the use of the term “diabetes in pregnancy” (2) for this group.

Cognizant that milder degrees of hyperglycemia would also be detected by early pregnancy testing, the IADPSG also recommended that fasting …

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Issues With the Diagnosis and Classification of Hyperglycemia in Early Pregnancy
H. David McIntyre, David A. Sacks, Linda A. Barbour, Denice S. Feig, Patrick M. Catalano, Peter Damm, Aidan McElduff
Diabetes Care Jan 2016, 39 (1) 53-54; DOI: 10.2337/dc15-1887

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Issues With the Diagnosis and Classification of Hyperglycemia in Early Pregnancy
H. David McIntyre, David A. Sacks, Linda A. Barbour, Denice S. Feig, Patrick M. Catalano, Peter Damm, Aidan McElduff
Diabetes Care Jan 2016, 39 (1) 53-54; DOI: 10.2337/dc15-1887
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  • The Comparative Effectiveness of Diabetes Prevention Strategies to Reduce Postpartum Weight Retention in Women With Gestational Diabetes Mellitus: The Gestational Diabetes’ Effects on Moms (GEM) Cluster Randomized Controlled Trial
  • Gestational Diabetes Mellitus Can Be Prevented by Lifestyle Intervention: The Finnish Gestational Diabetes Prevention Study (RADIEL)
  • Randomized Controlled Trial Investigating the Effects of a Low–Glycemic Index Diet on Pregnancy Outcomes in Women at High Risk of Gestational Diabetes Mellitus: The GI Baby 3 Study
Show more Considerations in the Management of Gestational Diabetes Mellitus

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