Comment on Jakubowicz et al. Fasting Until Noon Triggers Increased Postprandial Hyperglycemia and Impaired Insulin Response After Lunch and Dinner in Individuals With Type 2 Diabetes: A Randomized Clinical Trial. Diabetes Care 2015;38:1820–1826

More than 100 years ago, it was shown that oral ingestion of two successive carbohydrate meals results in an improved glucose tolerance in healthy people, a phenomenon known as the “Staub-Traugott” effect. In 1970, Metz and Friedenberg (1) reported that an improvement in glucose tolerance to sequential intravenous glucose loads could be seen in both subjects with normal glucose tolerance and with glucose intolerance after a second or even a third isocaloric glucose load. Much work was subsequently carried out to study the metabolic …