Diabetes Care: 41 (2)

February 01 2018; volume 41 issue 2

In This Issue

Open Access
In This Issue of Diabetes Care
Diabetes Care 2018 Feb; 41 (2): 207-208. https://doi.org/10.2337/dc18-ti02

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Perspectives in Care

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The National Diabetes Education Program at 20 Years: Lessons Learned and Plans for the Future
Linda M. Siminerio, Ann Albright, Judith Fradkin, Joanne Gallivan, Jude McDivitt, Betsy Rodríguez, Diane Tuncer and Faye Wong

Diabetes Care 2018 Feb; 41 (2): 209-218. https://doi.org/10.2337/dc17-0976

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Mortality Reduction in EMPA-REG OUTCOME Trial: Beyond the Antidiabetes Effect
Samy Suissa

Diabetes Care 2018 Feb; 41 (2): 219-223. https://doi.org/10.2337/dc17-1059

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Commentary

Open Access
Teasing Diabetes Apart, One Locus at a Time
R. David Leslie and Struan F.A. Grant

Diabetes Care 2018 Feb; 41 (2): 224-226. https://doi.org/10.2337/dci17-0046

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Norbert Freinkel Award Lecture

Open Access
Discovery, Knowledge, and Action—Diabetes in Pregnancy Across the Translational Spectrum: The 2016 Norbert Freinkel Award Lecture
H. David McIntyre

Diabetes Care 2018 Feb; 41 (2): 227-232. https://doi.org/10.2337/dci17-0056

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Kelly West Award Lecture

Open Access
Diabetes in Youth—Looking Backwards to Inform the Future: Kelly West Award Lecture 2017
Dana Dabelea

Diabetes Care 2018 Feb; 41 (2): 233-240. https://doi.org/10.2337/dci17-0031

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Profiles in Progress

Open Access
The Role of Diabetes Care and Its Contributions to the Field of Diabetes: A Profile in Progress
Lyn Reynolds and Saul M. Genuth

Diabetes Care 2018 Feb; 41 (2): 241-249. https://doi.org/10.2337/dci17-0021

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Clinical Care/Education/Nutrition/Psychosocial Research

Open Access
Five-Year Cost-effectiveness of the Multidisciplinary Risk Assessment and Management Programme–Diabetes Mellitus (RAMP-DM)
Fang Fang Jiao, Colman Siu Cheung Fung, Eric Yuk Fai Wan, Anca Ka Chun Chan, Sarah Morag McGhee, Ruby Lai Ping Kwok and Cindy Lo Kuen Lam

Diabetes Care 2018 Feb; 41 (2): 250-257. https://doi.org/10.2337/dc17-1149

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Efficacy and Safety of Once-Weekly Semaglutide Versus Exenatide ER in Subjects With Type 2 Diabetes (SUSTAIN 3): A 56-Week, Open-Label, Randomized Clinical Trial
Andrew J. Ahmann, Matthew Capehorn, Guillaume Charpentier, Francesco Dotta, Elena Henkel, Ildiko Lingvay, Anders G. Holst, Miriam P. Annett and Vanita R. Aroda

Diabetes Care 2018 Feb; 41 (2): 258-266. https://doi.org/10.2337/dc17-0417

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Predictors of Quality of Life and Other Patient-Reported Outcomes in the PANORAMA Multinational Study of People With Type 2 Diabetes
Clare Bradley, Eveline Eschwège, Pedro de Pablos-Velasco, Klaus G. Parhofer, Dominique Simon, Hans Vandenberghe and Linda Gönder-Frederick

Diabetes Care 2018 Feb; 41 (2): 267-276. https://doi.org/10.2337/dc16-2655

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Epidemiology/Health Services Research

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Interaction of Dietary and Genetic Factors Influencing Body Iron Status and Risk of Type 2 Diabetes Within the EPIC-InterAct Study
Karina Meidtner, Clara Podmore, Janine Kröger, Yvonne T. van der Schouw, Benedetta Bendinelli, Claudia Agnoli, Larraitz Arriola, Aurelio Barricarte, Heiner Boeing, Amanda J. Cross, Courtney Dow, Kim Ekblom, Guy Fagherazzi, Paul W. Franks, Marc J. Gunter, José María Huerta, Paula Jakszyn, Mazda Jenab, Verena A. Katzke, Timothy J. Key, Kay Tee Khaw, Tilman Kühn, Cecilie Kyrø, Francesca Romana Mancini, Olle Melander, Peter M. Nilsson, Kim Overvad, Domenico Palli, Salvatore Panico, J. Ramón Quirós, Miguel Rodríguez-Barranco, Carlotta Sacerdote, Ivonne Sluijs, Magdalena Stepien, Anne Tjonneland, Rosario Tumino, Nita G. Forouhi, Stephen J. Sharp, Claudia Langenberg, Matthias B. Schulze, Elio Riboli and Nicholas J. Wareham

Diabetes Care 2018 Feb; 41 (2): 277-285. https://doi.org/10.2337/dc17-1080

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Incretin-Based Therapies and the Short-term Risk of Pancreatic Cancer: Results From Two Retrospective Cohort Studies
Mathieu Boniol, Matteo Franchi, Maria Bota, Agnès Leclercq, Joeri Guillaume, Nancy van Damme, Giovanni Corrao, Philippe Autier and Peter Boyle

Diabetes Care 2018 Feb; 41 (2): 286-292. https://doi.org/10.2337/dc17-0280

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Declining Rates of Hospitalization for Selected Cardiovascular Disease Conditions Among Adults Aged ≥35 Years With Diagnosed Diabetes, U.S., 1998–2014
Nilka Ríos Burrows, YanFeng Li, Edward W. Gregg and Linda S. Geiss

Diabetes Care 2018 Feb; 41 (2): 293-302. https://doi.org/10.2337/dc17-1259

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Emerging Technologies and Therapeutics

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Reduction in Hypoglycemia With the Predictive Low-Glucose Management System: A Long-term Randomized Controlled Trial in Adolescents With Type 1 Diabetes
Mary B. Abraham, Jennifer A. Nicholas, Grant J. Smith, Janice M. Fairchild, Bruce R. King, Geoffrey R. Ambler, Fergus J. Cameron, Elizabeth A. Davis and Timothy W. Jones, on behalf of the PLGM Study Group

Diabetes Care 2018 Feb; 41 (2): 303-310. https://doi.org/10.2337/dc17-1604

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Pathophysiology/Complications

Open Access
TCF7L2 Genetic Variants Contribute to Phenotypic Heterogeneity of Type 1 Diabetes
Maria J. Redondo, Susan Geyer, Andrea K. Steck, Jay Sosenko, Mark Anderson, Peter Antinozzi, Aaron Michels, John Wentworth, Ping Xu, Alberto Pugliese and the Type 1 Diabetes TrialNet Study Group

Diabetes Care 2018 Feb; 41 (2): 311-317. https://doi.org/10.2337/dc17-0961

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Comparison of β-Cell Function Between Overweight/Obese Adults and Adolescents Across the Spectrum of Glycemia
Melinda E. Chen, Aaditya G. Chandramouli, Robert V. Considine, Tamara S. Hannon and Kieren J. Mather

Diabetes Care 2018 Feb; 41 (2): 318-325. https://doi.org/10.2337/dc17-1373

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Revisiting the Relationships Between Measures of Glycemic Control and Hypoglycemia in Continuous Glucose Monitoring Data Sets
Marga Gimenez, Amitai Jeremy Tannen, Monika Reddy, Vanessa Moscardo, Ignacio Conget and Nick Oliver

Diabetes Care 2018 Feb; 41 (2): 326-332. https://doi.org/10.2337/dc17-1597

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Cardiovascular and Metabolic Risk

Open Access
Efficacy and Safety of ITCA 650, a Novel Drug-Device GLP-1 Receptor Agonist, in Type 2 Diabetes Uncontrolled With Oral Antidiabetes Drugs: The FREEDOM-1 Trial
Julio Rosenstock, John B. Buse, Rehan Azeem, Prakash Prabhakar, Lise Kjems, Holly Huang and Michelle A. Baron

Diabetes Care 2018 Feb; 41 (2): 333-340. https://doi.org/10.2337/dc17-1306

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Cardiovascular Disease, Cancer, and Mortality Among People With Type 2 Diabetes and Alcoholic or Nonalcoholic Fatty Liver Disease Hospital Admission
Sarah H. Wild, Jeremy J. Walker, Joanne R. Morling, David A. McAllister, Helen M. Colhoun, Bassam Farran, Stuart McGurnaghan, Rory McCrimmon, Stephanie H. Read, Naveed Sattar and Christopher D. Byrne, on behalf of the Scottish Diabetes Research Network Epidemiology Group

Diabetes Care 2018 Feb; 41 (2): 341-347. https://doi.org/10.2337/dc17-1590

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Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD
Hetal S. Shah, Mario Luca Morieri, Santica M. Marcovina, Ronald J. Sigal, Hertzel C. Gerstein, Michael J. Wagner, Alison A. Motsinger-Reif, John B. Buse, Peter Kraft, Josyf C. Mychaleckyj and Alessandro Doria

Diabetes Care 2018 Feb; 41 (2): 348-355. https://doi.org/10.2337/dc17-1638

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Open Access
How Does Empagliflozin Reduce Cardiovascular Mortality? Insights From a Mediation Analysis of the EMPA-REG OUTCOME Trial
Silvio E. Inzucchi, Bernard Zinman, David Fitchett, Christoph Wanner, Ele Ferrannini, Martin Schumacher, Claudia Schmoor, Kristin Ohneberg, Odd Erik Johansen, Jyothis T. George, Stefan Hantel, Erich Bluhmki and John M. Lachin

Diabetes Care 2018 Feb; 41 (2): 356-363. https://doi.org/10.2337/dc17-1096

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Novel Communications in Diabetes

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Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors and Incident Type 2 Diabetes: A Systematic Review and Meta-analysis With Over 96,000 Patient-Years
Luiz Sérgio F. de Carvalho, Alessandra M. Campos and Andrei C. Sposito

Diabetes Care 2018 Feb; 41 (2): 364-367. https://doi.org/10.2337/dc17-1464

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Increased Liver Fatty Acid Uptake Is Partly Reversed and Liver Fat Content Normalized After Bariatric Surgery
Heidi Immonen, Jarna C. Hannukainen, Nobuyuki Kudomi, Jussi Pihlajamäki, Virva Saunavaara, Jukka Laine, Paulina Salminen, Terho Lehtimäki, Tam Pham, Patricia Iozzo and Pirjo Nuutila

Diabetes Care 2018 Feb; 41 (2): 368-371. https://doi.org/10.2337/dc17-0738

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Meta-analysis

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Nonalcoholic Fatty Liver Disease and Risk of Incident Type 2 Diabetes: A Meta-analysis
Alessandro Mantovani, Christopher D. Byrne, Enzo Bonora and Giovanni Targher

Diabetes Care 2018 Feb; 41 (2): 372-382. https://doi.org/10.2337/dc17-1902

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Issues and Events

Open Access
Issues and Events
Diabetes Care 2018 Feb; 41 (2): 383. https://doi.org/10.2337/dc18-ie02

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e-Letters

Observations
- Open Access
  Morning Enzymatic Activity of DPP-4 Is Differentially Altered by Sleep Loss in Women and Men
  Frida H. Rångtell, Felix Schmidt, Josefine Würfel, Swathy Karamchedu, Peter Andersson, Heike Vogel and Christian Benedict
  
  Diabetes Care 2018 Feb; 41 (2): e10-e11. https://doi.org/10.2337/dc17-1762
  
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- Open Access
  Obstructive Sleep Apnea and Diabetes Independently Add to Cardiovascular Risk After Coronary Revascularization
  Chieh Yang Koo, Luciano F. Drager, Rishi Sethi, Hee-Hwa Ho, Thet Hein, Man-Hong Jim, Bee-Choo Tai, Jun-Jie Zhang and Chi-Hang Lee, on behalf of the Sleep and Stent Study Investigators
  
  Diabetes Care 2018 Feb; 41 (2): e12-e14. https://doi.org/10.2337/dc17-0759
  
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- Open Access
  Twin Pregnancy With Gestational Diabetes Mellitus: A Double Whammy?
  Sara Ooi and Vincent W. Wong
  
  Diabetes Care 2018 Feb; 41 (2): e15-e16. https://doi.org/10.2337/dc17-2227
  
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Comments and Responses
- Open Access
  Comment on Edelman and Polonsky. Type 2 Diabetes in the Real World: The Elusive Nature of Glycemic Control. Diabetes Care 2017;40:1425–1432
  Dario Giugliano, Maria Ida Maiorino, Giuseppe Bellastella and Katherine Esposito
  
  Diabetes Care 2018 Feb; 41 (2): e17. https://doi.org/10.2337/dc17-1826
  
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- Open Access
  Response to Comment on Edelman and Polonsky. Type 2 Diabetes in the Real World: The Elusive Nature of Glycemic Control. Diabetes Care 2017;40:1425–1432
  Steven V. Edelman and William H. Polonsky
  
  Diabetes Care 2018 Feb; 41 (2): e18. https://doi.org/10.2337/dci17-0050
  
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- Open Access
  Comment on Lent et al. All-Cause and Specific-Cause Mortality Risk After Roux-en-Y Gastric Bypass in Patients With and Without Diabetes. Diabetes Care 2017;40:1379–1385
  Antonio E. Pontiroli and Ahmed S. Zakaria
  
  Diabetes Care 2018 Feb; 41 (2): e19. https://doi.org/10.2337/dc17-1895
  
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- Open Access
  Response to comment on Lent et al. All-Cause and Specific-Cause Mortality Risk After Roux-en-Y Gastric Bypass in Patients With and Without Diabetes. Diabetes Care 2017;40:1379–1385
  Michelle R. Lent, Peter N. Benotti and G. Craig Wood
  
  Diabetes Care 2018 Feb; 41 (2): e20. https://doi.org/10.2337/dci17-0055
  
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Table of Contents

In This Issue

Perspectives in Care

Commentary

Norbert Freinkel Award Lecture

Kelly West Award Lecture

Profiles in Progress

Clinical Care/Education/Nutrition/Psychosocial Research

Epidemiology/Health Services Research

Emerging Technologies and Therapeutics

Pathophysiology/Complications

Cardiovascular and Metabolic Risk

Novel Communications in Diabetes

Meta-analysis

Issues and Events

e-Letters

Observations

Comments and Responses

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