Emerging Therapies: Drugs and Regimens

Sitagliptin Treatment at the Time of Hospitalization Was Associated With Reduced Mortality in Patients With Type 2 Diabetes and COVID-19: A Multicenter, Case-Control, Retrospective, Observational Study

  1. Sebastiano Bruno Solerte1,2,
  2. Francesca D’Addio3,
  3. Roberto Trevisan4,
  4. Elisabetta Lovati5,
  5. Antonio Rossi6,
  6. Ida Pastore6,
  7. Marco Dell’Acqua3,6,
  8. Elio Ippolito3,
  9. Cristiana Scaranna4,
  10. Rosalia Bellante4,
  11. Silvia Galliani4,
  12. Alessandro Roberto Dodesini4,
  13. Giuseppe Lepore4,
  14. Francesca Geni1,2,
  15. Roberta Maria Fiorina3,
  16. Emanuele Catena7,
  17. Angelo Corsico8,
  18. Riccardo Colombo7,
  19. Marco Mirani9,
  20. Carlo De Riva10,
  21. Salvatore Endrio Oleandri11,
  22. Reza Abdi12,
  23. Joseph V. Bonventre12,
  24. Stefano Rusconi13,14,
  25. Franco Folli15,
  26. Antonio Di Sabatino5,
  27. Gianvincenzo Zuccotti16,17,
  28. Massimo Galli13,14 and
  29. Paolo Fiorina3,6,18⇑
  1. 1Department of Internal Medicine, Geriatric and Diabetology Unit, University of Pavia, Italy
  2. 2School of Geriatrics, University of Pavia Azienda di Servizi alla Persona-Pavia, Pavia, Italy
  3. 3International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, Dipartimento di Scienze Biomediche e Cliniche L. Sacco, Università di Milano, Milan, Italy
  4. 4Unità Operativa Complessa Malattie Endocrine 1-Diabetologia, Ospedale Papa Giovanni XXIII Azienda Socio Sanitaria Territoriale-PG XXIII, Bergamo, Italy
  5. 5Internal Medicine Unit, University of Pavia and IRCCS Policlinico San Matteo, Pavia, Italy
  6. 6Division of Endocrinology, Azienda Socio Sanitaria Territoriale Fatebenefratelli Sacco, Milan, Italy
  7. 7Department of Anesthesia and Intensive Care Unit, Azienda Socio Sanitaria Territoriale Fatebenefratelli Sacco, Luigi Sacco Hospital, Università di Milano, Milan, Italy
  8. 8Pneumology Unit, Fondazione IRCCS Policlinico San Matteo and Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
  9. 9Endocrinology and Diabetology Unit, Humanitas Research Hospital, Rozzano, Milan, Italy
  10. 10Unità Operativa di Malattie Endocrine ULSS3-Ospedale dell’Angelo Mestre, Mestre, Italy
  11. 11Department of Endocrinology and Metabolism, Azienda Sanitaria Locale Città di Torino, Torino, Italy
  12. 12Renal Division, Brigham and Women’s Hospital, Boston, MA
  13. 13Department of Biomedical and Clinical Sciences “Luigi Sacco,” Univeristà di Milano, Milan, Italy
  14. 14III Division of Infectious Diseases, Azienda Socio Sanitaria Territoriale Fatebenefratelli Sacco, Luigi Sacco Hospital, Milan, Italy
  15. 15Endocrinology and Metabolism, Department of Health Science, Università di Milano, Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo, Milan, Italy
  16. 16Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, Dipartimento di Scienze Biomediche e Cliniche, Università di Milano, Milan, Italy
  17. 17Department of Pediatrics, “V. Buzzi” Children's Hospital, Milan, Italy
  18. 18Division of Nephrology, Boston Children’s Hospital, Harvard Medical School, Boston, MA
  1. Corresponding author: Paolo Fiorina, paolo.fiorina{at}childrens.harvard.edu

  1. S.B.S. and F.D’A. are co-first authors.

Diabetes Care 2020 Dec; 43(12): 2999-3006. https://doi.org/10.2337/dc20-1521

Data supplements

  • Supplemental material, Fiorina, et al.

    Supplemental material is available at https://doi.org/10.2337/figshare.12907490.
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    Sitagliptin Treatment at the Time of Hospitalization Was Associated With Reduced Mortality in Patients With Type 2 Diabetes and COVID-19: A Multicenter, Case-Control, Retrospective, Observational Study
    Sebastiano Bruno Solerte, Francesca D’Addio, Roberto Trevisan, Elisabetta Lovati, Antonio Rossi, Ida Pastore, Marco Dell’Acqua, Elio Ippolito, Cristiana Scaranna, Rosalia Bellante, Silvia Galliani, Alessandro Roberto Dodesini, Giuseppe Lepore, Francesca Geni, Roberta Maria Fiorina, Emanuele Catena, Angelo Corsico, Riccardo Colombo, Marco Mirani, Carlo De Riva, Salvatore Endrio Oleandri, Reza Abdi, Joseph V. Bonventre, Stefano Rusconi, Franco Folli, Antonio Di Sabatino, Gianvincenzo Zuccotti, Massimo Galli, Paolo Fiorina
    Diabetes Care Dec 2020, 43 (12) 2999-3006; DOI: 10.2337/dc20-1521
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