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Emerging Therapies: Drugs and Regimens

Efficacy and Safety of Liraglutide 3.0 mg in Individuals With Overweight or Obesity and Type 2 Diabetes Treated With Basal Insulin: The SCALE Insulin Randomized Controlled Trial

  1. W. Timothy Garvey1⇑,
  2. Andreas L. Birkenfeld2,3,4,
  3. Dror Dicker5,6,
  4. Geltrude Mingrone4,7,8,
  5. Sue D. Pedersen9,
  6. Altynai Satylganova10,
  7. Dorthe Skovgaard10,
  8. Danny Sugimoto11,
  9. Camilla Jensen10 and
  10. Ofri Mosenzon12
  1. 1Department of Nutrition Sciences, The University of Alabama at Birmingham and the Birmingham VA Medical Center, Birmingham, AL
  2. 2Department of Diabetology, Endocrinology, and Nephrology, Eberhard Karls University Tübingen, Tübingen, Germany
  3. 3Institute for Diabetes Research and Metabolic Diseases, Helmholtz Centre Munich at the University of Tübingen, Tübingen, Germany
  4. 4Division of Diabetes and Nutritional Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, U.K.
  5. 5Internal Medicine D, Hasharon Hospital, Rabin Medical Center, Petah Tikva, Israel
  6. 6Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
  7. 7Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
  8. 8Università Cattolica del Sacro Cuore, Rome, Italy
  9. 9C-ENDO Diabetes and Endocrinology Clinic, Calgary, Alberta, Canada
  10. 10Novo Nordisk A/S, Søborg, Denmark
  11. 11Cedar Crosse Research Center, Chicago, IL
  12. 12Diabetes Unit, Department of Internal Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel
  1. Corresponding author: W. Timothy Garvey, garveyt{at}uab.edu
Diabetes Care 2020 May; 43(5): 1085-1093. https://doi.org/10.2337/dc19-1745
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Article Information

vol. 43 no. 5 1085-1093
DOI 
https://doi.org/10.2337/dc19-1745
PubMed 
32139381

Published By 
American Diabetes Association
Print ISSN 
0149-5992
Online ISSN 
1935-5548
History 
  • Received August 30, 2019
  • Accepted February 13, 2020
  • Published in print April 20, 2020.
  • Published online ahead of print March 5, 2020.

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  • Previous version (March 5, 2020 - 08:52).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2020 by the American Diabetes Association https://www.diabetesjournals.org/content/licenseReaders may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at https://www.diabetesjournals.org/content/license.

Author Information

  1. W. Timothy Garvey1⇑,
  2. Andreas L. Birkenfeld2,3,4,
  3. Dror Dicker5,6,
  4. Geltrude Mingrone4,7,8,
  5. Sue D. Pedersen9,
  6. Altynai Satylganova10,
  7. Dorthe Skovgaard10,
  8. Danny Sugimoto11,
  9. Camilla Jensen10 and
  10. Ofri Mosenzon12
  1. 1Department of Nutrition Sciences, The University of Alabama at Birmingham and the Birmingham VA Medical Center, Birmingham, AL
  2. 2Department of Diabetology, Endocrinology, and Nephrology, Eberhard Karls University Tübingen, Tübingen, Germany
  3. 3Institute for Diabetes Research and Metabolic Diseases, Helmholtz Centre Munich at the University of Tübingen, Tübingen, Germany
  4. 4Division of Diabetes and Nutritional Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, U.K.
  5. 5Internal Medicine D, Hasharon Hospital, Rabin Medical Center, Petah Tikva, Israel
  6. 6Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
  7. 7Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
  8. 8Università Cattolica del Sacro Cuore, Rome, Italy
  9. 9C-ENDO Diabetes and Endocrinology Clinic, Calgary, Alberta, Canada
  10. 10Novo Nordisk A/S, Søborg, Denmark
  11. 11Cedar Crosse Research Center, Chicago, IL
  12. 12Diabetes Unit, Department of Internal Medicine, Hadassah Hebrew University Hospital, Jerusalem, Israel
  1. Corresponding author: W. Timothy Garvey, garveyt{at}uab.edu
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Efficacy and Safety of Liraglutide 3.0 mg in Individuals With Overweight or Obesity and Type 2 Diabetes Treated With Basal Insulin: The SCALE Insulin Randomized Controlled Trial
W. Timothy Garvey, Andreas L. Birkenfeld, Dror Dicker, Geltrude Mingrone, Sue D. Pedersen, Altynai Satylganova, Dorthe Skovgaard, Danny Sugimoto, Camilla Jensen, Ofri Mosenzon
Diabetes Care May 2020, 43 (5) 1085-1093; DOI: 10.2337/dc19-1745

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Efficacy and Safety of Liraglutide 3.0 mg in Individuals With Overweight or Obesity and Type 2 Diabetes Treated With Basal Insulin: The SCALE Insulin Randomized Controlled Trial
W. Timothy Garvey, Andreas L. Birkenfeld, Dror Dicker, Geltrude Mingrone, Sue D. Pedersen, Altynai Satylganova, Dorthe Skovgaard, Danny Sugimoto, Camilla Jensen, Ofri Mosenzon
Diabetes Care May 2020, 43 (5) 1085-1093; DOI: 10.2337/dc19-1745
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  • Durable Effects of iGlarLixi Up to 52 Weeks in Type 2 Diabetes: The LixiLan-G Extension Study
  • Efficacy and Safety of Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg in Metformin-Treated Patients With Type 2 Diabetes in a Randomized Controlled Trial (AWARD-11)
  • Pharmacokinetics and Pharmacodynamics of Three Different Formulations of Insulin Aspart: A Randomized, Double-Blind, Crossover Study in Men With Type 1 Diabetes
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© 2021 by the American Diabetes Association. Diabetes Care Print ISSN: 0149-5992, Online ISSN: 1935-5548.